SUMOylation of NOP58 with SUMO1

Stable Identifier
R-HSA-4570467
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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NOP58 (NOP5) is SUMOylated at lysine-467 and lysine-497 with SUMO1 (Matafora et al. 2009, Westman et al. 2010, Westman and Lamond 2011,Impens et al. 2014). SUMOylation is required for binding of snoRNAs by NOP58.

Literature References
PubMed ID Title Journal Year
12196509 Proteomic analysis of the mammalian nuclear pore complex

Cronshaw, JM, Krutchinsky, AN, Zhang, W, Chait, BT, Matunis, MJ

J Cell Biol 2002
19596686 Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition

Matafora, V, D'Amato, A, Mori, S, Blasi, F, Bachi, A

Mol. Cell Proteomics 2009
20797632 A proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58

Westman, BJ, Verheggen, C, Hutten, S, Lam, YW, Bertrand, E, Lamond, AI

Mol. Cell 2010
25114211 Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli

Impens, F, Radoshevich, L, Cossart, P, Ribet, D

Proc. Natl. Acad. Sci. U.S.A. 2014
21647297 A role for SUMOylation in snoRNP biogenesis revealed by quantitative proteomics

Westman, BJ, Lamond, AI

Nucleus 2011
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
SUMO transferase activity of SUMO1:C93-UBE2I [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created