RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1

Stable Identifier
R-HSA-4570493
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm, nuclear envelope
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
RANBP2 (NUP358) SUMOylates HNRNPC at lysine-237 of isoform C1 (lysine-250 of the reference isoform C2) with SUMO1 (Vassileva et al. 2004). SUMOylation decreases the interaction of HNRNPC with single-stranded DNA.
Literature References
PubMed ID Title Journal Year
15082759 SUMO modification of heterogeneous nuclear ribonucleoproteins

Vassileva, MT, Matunis, MJ

Mol. Cell. Biol. 2004
Participants
Input
Output
Participates
as an event of
Catalyst Activity

SUMO transferase activity of Nuclear Pore Complex (NPC) [nuclear envelope]

Physical Entity
Nuclear Pore Complex (NPC) [nuclear envelope] (Homo sapiens)
Activity
SUMO transferase activity (GO:0019789)
Orthologous Events
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Bos taurus)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Mus musculus)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Rattus norvegicus)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Saccharomyces cerevisiae)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Schizosaccharomyces pombe)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Sus scrofa)
RANBP2 (NUP358) SUMOylates HNRNPC with SUMO1 (Xenopus tropicalis)
Authored
May, B  (2013-09-19)
Reviewed
Filosa, G  (2015-10-17)
Bachi, A  (2015-10-17)
Created
May, B  (2013-09-21)
Cite Us!