monoSUMO1-K75-SUZ12 [nucleoplasm]

Stable Identifier
R-HSA-4615932
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Polycomb protein SUZ12, SUZ12_HUMAN
Icon
monoSUMO1-K75-SUZ12 [nucleoplasm] icon
monoSUMO1-K75-SUZ12 [nucleoplasm] icon
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:Q15022 SUZ12
Gene Names
SUZ12, CHET9, JJAZ1, KIAA0160
Chain
chain:1-739
Reference Genes
BioGPS Gene:23512 SUZ12
COSMIC (genes):SUZ12 SUZ12
CTD Gene:23512 SUZ12
dbSNP Gene:23512 SUZ12
ENSEMBL:ENSG00000178691 SUZ12
ENSEMBL_homo_sapiens_GENE:ENSG00000178691.11 SUZ12
HGNC:17101 SUZ12
KEGG Gene (Homo sapiens):23512 SUZ12
Monarch:23512 SUZ12
NCBI Gene:23512 SUZ12
OMIM:606245 SUZ12
UCSC:Q15022 SUZ12
Reference Transcript
Other Identifiers
11739485_a_at
11739486_at
11739487_s_at
16833037
212287_PM_at
212287_at
213971_PM_s_at
213971_s_at
23512
3716676
3716682
3716685
3716687
3717399
3717400
3717401
3717402
3717403
3717406
3717407
3717411
3717413
3717415
3717417
3717418
3717420
3717422
3717424
3717425
3717426
3717428
3717430
3717431
3717432
3717433
40957_at
8006325
A_14_P109382
A_23_P100883
A_32_P24223
D63881_at
GE81999
GO:0000122
GO:0000978
GO:0001222
GO:0001739
GO:0003677
GO:0003682
GO:0003723
GO:0003824
GO:0005515
GO:0005634
GO:0005654
GO:0005677
GO:0005694
GO:0005730
GO:0006325
GO:0006351
GO:0006355
GO:0008047
GO:0008283
GO:0008284
GO:0016586
GO:0016604
GO:0016740
GO:0030154
GO:0031490
GO:0032993
GO:0035064
GO:0035098
GO:0036211
GO:0042054
GO:0042393
GO:0043226
GO:0043565
GO:0045596
GO:0046872
GO:0048709
GO:0048856
GO:0060816
GO:0098772
GO:0106222
GO:0140096
GO:0140718
GO:1990841
GO:1990904
HMNXSV003041554
HMNXSV003057700
Hs.197803.0.A1_3p_at
Hs.197803.1.A1_3p_a_at
Hs.197803.1.A1_3p_x_at
ILMN_1797813
PH_hs_0023866
TC17000369.hg
Participates
as an output of
Other forms of this molecule
SUZ12 [nucleoplasm]
Inferred To
suz12b [nucleoplasm] (Danio rerio)
Suz12 [nucleoplasm] (Mus musculus)
Suz12 [nucleoplasm] (Rattus norvegicus)
SWP82 [nucleoplasm] (Saccharomyces cerevisiae)
suz12 [nucleoplasm] (Xenopus tropicalis)
SUZ12 [nucleoplasm] (Bos taurus)
SUZ12 [nucleoplasm] (Sus scrofa)
rsc7 [nucleoplasm] (Schizosaccharomyces pombe)
Modified Residues
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at 75
Coordinate
75
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
RefSeq
OpenTargets
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
Orphanet
PDB
Interactors (24)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q15910 EZH2  1 0.957 31
 UniProt:O75530 EED  1 0.909 12
 UniProt:Q6ZN18 AEBP2  1 0.881 10
 UniProt:Q16576 RBBP7  1 0.837 10
 UniProt:Q09028 RBBP4  1 0.837 9
 UniProt:Q92833 JARID2  1 0.788 7
 UniProt:Q92800 EZH1      0.725 6
 UniProt:O43189 PHF1  1 0.725 7
 UniProt:Q9Y483 MTF2  1 0.725 6
 UniProt:Q96JN0 LCOR      0.706 6
 UniProt:Q5T6S3 PHF19  1 0.643 6
 UniProt:A6NHQ4 EPOP      0.643 5
 UniProt:Q13620 CUL4B  2 0.597 13
 UniProt:Q92833-1 JARID2      0.558 7
 UniProt:Q1XH10 SKDA1      0.527 2
 UniProt:Q5VWX1 KHDRBS2  2 0.527 2
 UniProt:P62249 RPS16  2 0.527 2
 UniProt:O15379 HDAC3  2 0.499 7
 UniProt:Q15156 Q15156      0.499 6
 UniProt:O75530-1 EED      0.488 2
 UniProt:Q14774 HLX      0.471 2
 UniProt:Q9UBC3 DNMT3B  2 0.462 2
 UniProt:Q16531 DDB1  1 0.462 10
 UniProt:P01106 MYC  2 0.462 4
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