AXIN is ubiquitinated by SMURF2

Stable Identifier
R-HSA-4641129
Type
Reaction
Species
Homo sapiens
Compartment
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SMURF2 has been shown to ubiquitinate AXIN at lysine 505 both in vitro and in vivo in a manner that depends on the interaction between the two proteins (Kim and Jho, 2012).

Literature References
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ubiquitin protein ligase activity of AXIN:SMURF2 [cytosol]
Physical Entity
Activity
Orthologous Events
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