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LGR4 [plasma membrane]
Stable Identifier
R-HSA-4641169
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
GPR48
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Regulation of FZD by ubiquitination (Homo sapiens)
RSPO:LGR binds ZNRF3 (Homo sapiens)
RSPO:LGR [plasma membrane] (Homo sapiens)
LGR [plasma membrane] (Homo sapiens)
LGR4 [plasma membrane] (Homo sapiens)
RSPO:LGR:ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
RSPO:LGR [plasma membrane] (Homo sapiens)
LGR [plasma membrane] (Homo sapiens)
LGR4 [plasma membrane] (Homo sapiens)
RSPOs bind LGRs (Homo sapiens)
LGR [plasma membrane] (Homo sapiens)
LGR4 [plasma membrane] (Homo sapiens)
RSPO:LGR [plasma membrane] (Homo sapiens)
LGR [plasma membrane] (Homo sapiens)
LGR4 [plasma membrane] (Homo sapiens)
ZNRF3 autoubiquitinates to promote its internalization (Homo sapiens)
RSPO:LGR:ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
RSPO:LGR [plasma membrane] (Homo sapiens)
LGR [plasma membrane] (Homo sapiens)
LGR4 [plasma membrane] (Homo sapiens)
RSPO:LGR:ub-ZNRF3,RNF43 [plasma membrane] (Homo sapiens)
LGR [plasma membrane] (Homo sapiens)
LGR4 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BXB1 LGR4
Gene Names
LGR4, GPR48
Chain
signal peptide:1-24, chain:25-951
Reference Genes
BioGPS Gene:55366 LGR4
COSMIC (genes):LGR4 LGR4
CTD Gene:55366 LGR4
dbSNP Gene:55366 LGR4
ENSEMBL:ENSG00000205213 LGR4
ENSEMBL_homo_sapiens_GENE:ENSG00000205213.14 LGR4
HGNC:13299 LGR4
KEGG Gene (Homo sapiens):55366 LGR4
Monarch:55366 LGR4
NCBI Gene:55366 LGR4
OMIM:606666 LGR4
UCSC:Q9BXB1 LGR4
Reference Transcript
RefSeq:NM_018490.3 LGR4
RefSeq:NM_001346432.1 LGR4
Other Identifiers
11743625_a_at
11743626_s_at
16736821
218326_3p_s_at
218326_PM_s_at
218326_s_at
222596_3p_s_at
222596_PM_s_at
222596_s_at
3367095
3367097
3367098
3367099
3367100
3367101
3367102
3367103
3367104
3367105
3367106
3367108
3367109
3367111
3367112
3367113
3367114
3367116
3367119
3367121
3367122
3367123
3367126
3367127
3367130
3367132
3367141
3367167
3367168
3367169
3367170
3367171
3367172
55366
61635_s_at
63874_at
78317_r_at
7947199
A_24_P90216
GE62336
GO:0001649
GO:0001818
GO:0001942
GO:0002376
GO:0004888
GO:0004930
GO:0005515
GO:0005886
GO:0006351
GO:0006355
GO:0007165
GO:0007186
GO:0007189
GO:0007283
GO:0007623
GO:0008528
GO:0016020
GO:0016055
GO:0016500
GO:0022414
GO:0023052
GO:0030154
GO:0030282
GO:0030539
GO:0032922
GO:0034122
GO:0035239
GO:0036335
GO:0045087
GO:0045892
GO:0045893
GO:0046849
GO:0048511
GO:0048565
GO:0048856
GO:0050673
GO:0060089
GO:0061290
GO:0072202
GO:0072224
GO:0072282
GO:0090190
GO:0090263
GO:0098542
GO:0120163
GO:2001013
HMNXSV003016742
Hs.160271.0.S1_3p_a_at
ILMN_1710408
PH_hs_0009752
TC11001509.hg
g8923700_3p_a_at
Participates
as a member of
LGR [plasma membrane] (Homo sapiens)
Inferred To
LGR4 [plasma membrane]
(Canis familiaris)
LGR4 [plasma membrane]
(Gallus gallus)
LGR4 [plasma membrane]
(Sus scrofa)
lgr4 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001333361.1
,
NP_060960.2
Guide to Pharmacology - Targets
147
OpenTargets
ENSG00000205213
GeneCards
Q9BXB1
HPA
ENSG00000205213-LGR4
Ensembl
ENSG00000205213
,
ENSP00000368516
,
ENST00000379214
,
ENSP00000374508
,
ENST00000389858
PRO
Q9BXB1
Pharos - Targets
Q9BXB1
PDB
4QXE
,
4QXF
,
4KT1
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