TOP1 [nucleoplasm]

Stable Identifier
R-HSA-4641363
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
DNA topoisomerase 1 ecNumber5.99.1.2/ecNumber, TOP1_HUMAN
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
TOP1
Chain
initiator methionine:1, chain:2-765
Reference Transcript
Other Identifiers
0002060670
1030_s_at
11717437_x_at
11717438_x_at
11717439_s_at
16913737
1710_s_at
208900_s_at
208901_s_at
2367108
2367109
2367112
2367113
31680_at
3885463
3885465
3885466
3885467
3885468
3885469
3885490
3885491
3885497
3885498
3885499
3885500
3885502
3885507
3885509
3885511
3885512
3885513
3885515
3885517
3885518
3885520
3885521
3885522
3885525
3885526
3885527
3885528
7150
8062603
A_23_P305507
A_33_P3371493
GE57478
GE60513
GO:0000228
GO:0000932
GO:0000978
GO:0001650
GO:0003674
GO:0003677
GO:0003682
GO:0003690
GO:0003697
GO:0003723
GO:0003916
GO:0003917
GO:0004674
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0005737
GO:0006259
GO:0006260
GO:0006265
GO:0006338
GO:0006464
GO:0007059
GO:0007623
GO:0008150
GO:0008219
GO:0009058
GO:0009790
GO:0012501
GO:0016032
GO:0016301
GO:0016310
GO:0016853
GO:0018105
GO:0019904
GO:0031298
GO:0032922
GO:0032991
GO:0032993
GO:0034641
GO:0040016
GO:0042493
GO:0043167
GO:0043204
GO:0043226
GO:0044403
GO:0048511
GO:0048856
GO:0051276
GO:0051301
GO:0097100
Hs.317.0.S1_3p_a_at
ILMN_1735572
ILMN_1763419
ILMN_2192316
PH_hs_0040753
TC20000302.hg
TC20001221.hg
U07804_s_at
U07806_s_at
g339805_3p_a_at
Participant Of
Other forms of this molecule
Inferred To
Cross References
RefSeq
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
ZINC - Investigational
GeneCards
ZINC - Predictions - Purchasable
Interactors (28)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P03070 LT      0.734 12
 UniProt:Q99801 NKX31      0.626 6
 UniProt:P00519 ABL1  5 0.602 7
 UniProt:P19338 NCL  1 0.59 3
 UniProt:P01106 MYC  2 0.564 2
 UniProt:P19320 VCAM1  1 0.527 4
 UniProt:P16403 H1-2  1 0.462 3
 UniProt:P09874 PARP1  4 0.462 3
 UniProt:Q92841 DDX17  2 0.462 3
 UniProt:P09651 HNRNPA1  1 0.462 3
 UniProt:P03372 ESR1  8 0.462 2
 UniProt:Q07955 SRSF1  1 0.462 3
 UniProt:P78527 PRKDC  4 0.462 2
 UniProt:Q15717 ELAVL1  6 0.462 3
 UniProt:Q08211 DHX9  2 0.462 3
 UniProt:P61978 HNRNPK  2 0.462 2
 UniProt:Q15233 NONO      0.462 2
 UniProt:Q6P2Q9 PRPF8  1 0.462 2
 UniProt:P22626 HNRNPA2B1  2 0.462 3
 UniProt:P09661 SNRPA1  1 0.462 2
 UniProt:P11388 TOP2A  3 0.462 3
 UniProt:O43390 HNRNPR  1 0.462 3
 UniProt:O75643 SNRNP200  1 0.462 2
 UniProt:P06748 NPM1  5 0.462 3
 UniProt:Q9NR30 DDX21  1 0.462 3
 UniProt:P07910 HNRNPC  2 0.462 3
 UniProt:Q00839 HNRNPU  1 0.462 3
 UniProt:P23246 SFPQ  3 0.462 2
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