TOP1 [nucleoplasm]

Stable Identifier
R-HSA-4641363
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
DNA topoisomerase 1 ecNumber5.99.1.2/ecNumber, TOP1_HUMAN
Locations in the PathwayBrowser for interactor UniProt:Q00839 HNRNPU
External Reference Information
External Reference
Gene Names
TOP1
Chain
initiator methionine:1, chain:2-765
Reference Transcript
Other Identifiers
0002060670
1030_s_at
11717437_x_at
11717438_x_at
11717439_s_at
16913737
1710_s_at
208900_s_at
208901_s_at
2367108
2367109
2367112
2367113
31680_at
3885463
3885465
3885466
3885467
3885468
3885469
3885490
3885491
3885497
3885498
3885499
3885500
3885502
3885507
3885509
3885511
3885512
3885513
3885515
3885517
3885518
3885520
3885521
3885522
3885525
3885526
3885527
3885528
8062603
A_23_P305507
A_33_P3371493
GE57478
GE60513
GO:0000228
GO:0000932
GO:0000978
GO:0001650
GO:0003674
GO:0003677
GO:0003682
GO:0003690
GO:0003697
GO:0003723
GO:0003916
GO:0003917
GO:0004674
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0005737
GO:0006259
GO:0006260
GO:0006265
GO:0006338
GO:0006464
GO:0007059
GO:0007623
GO:0008150
GO:0008219
GO:0009058
GO:0009790
GO:0012501
GO:0016032
GO:0016301
GO:0016310
GO:0016853
GO:0018105
GO:0019904
GO:0031298
GO:0032922
GO:0032991
GO:0032993
GO:0034641
GO:0040016
GO:0042493
GO:0043167
GO:0043204
GO:0043226
GO:0044403
GO:0048511
GO:0048856
GO:0051276
GO:0051301
GO:0097100
Hs.317.0.S1_3p_a_at
ILMN_1735572
ILMN_1763419
ILMN_2192316
PH_hs_0040753
TC20000302.hg
TC20001221.hg
U07804_s_at
U07806_s_at
g339805_3p_a_at
Participant Of
Other forms of this molecule
Inferred To
Cross References
RefSeq
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
ZINC - Investigational
GeneCards
ZINC - Predictions - Purchasable
Interactors (28)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P03070 LT      0.734 12
 UniProt:Q99801 NKX31      0.626 6
 UniProt:P00519 ABL1  5 0.602 7
 UniProt:P19338 NCL  1 0.59 3
 UniProt:P01106 MYC  2 0.564 2
 UniProt:P19320 VCAM1  1 0.527 4
 UniProt:P16403 H1-2  1 0.462 3
 UniProt:P09651 HNRNPA1  1 0.462 3
 UniProt:P03372 ESR1  8 0.462 2
 UniProt:P61978 HNRNPK  2 0.462 2
 UniProt:Q15233 NONO      0.462 2
 UniProt:Q6P2Q9 PRPF8  1 0.462 2
 UniProt:O75643 SNRNP200  1 0.462 2
 UniProt:Q9NR30 DDX21  1 0.462 3
 UniProt:P09874 PARP1  4 0.462 3
 UniProt:Q92841 DDX17  2 0.462 3
 UniProt:Q15717 ELAVL1  6 0.462 3
 UniProt:Q07955 SRSF1  1 0.462 3
 UniProt:P09661 SNRPA1  1 0.462 2
 UniProt:P11388 TOP2A  3 0.462 3
 UniProt:P78527 PRKDC  4 0.462 2
 UniProt:Q00839 HNRNPU  1 0.462 3
 UniProt:Q08211 DHX9  2 0.462 3
 UniProt:P22626 HNRNPA2B1  2 0.462 3
 UniProt:P07910 HNRNPC  2 0.462 3
 UniProt:P23246 SFPQ  3 0.462 2
 UniProt:P06748 NPM1  5 0.462 3
 UniProt:O43390 HNRNPR  1 0.462 3