BIRC5 [nucleoplasm]

Stable Identifier
R-HSA-4655344
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Survivin, Baculoviral IAP repeat-containing protein 5, Apoptosis inhibitor survivin, Apoptosis inhibitor 4
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:O15392 BIRC5
Gene Names
BIRC5, API4, IAP4
Chain
chain:1-142
Reference Genes
BioGPS Gene:332 BIRC5
COSMIC (genes):BIRC5 BIRC5
CTD Gene:332 BIRC5
dbSNP Gene:332 BIRC5
ENSEMBL:ENSG00000089685 BIRC5
HGNC:593 BIRC5
KEGG Gene (Homo sapiens):332 BIRC5
Monarch:332 BIRC5
NCBI Gene:332 BIRC5
OMIM:603352 BIRC5
UCSC:O15392 BIRC5
Reference Transcript
Other Identifiers
0002120152
11733864_a_at
11739602_a_at
11739603_x_at
11739653_a_at
11747720_a_at
11754109_s_at
11754110_x_at
11759736_a_at
11759737_x_at
11760008_at
11763580_x_at
16838359
202094_at
202095_s_at
210334_x_at
332
3736291
3736292
3736293
3736294
3736295
3736296
3736299
3736301
3736303
3736304
3736305
3736306
3736307
3736308
3736309
3736310
3736311
3736312
3736314
3736316
40532_at
4270
8010260
A0A0B4J1S3
A_14_P100099
A_23_P118815
BIRC5
BIRC5-203
BIRC5-207
BIRC5-208
BIRC5-211
CAB004270
CCDS32751
ENSG00000089685
ENSP00000364086
ENSP00000465868
ENSP00000466617
ENSP00000467336
ENST00000374948
ENST00000374948.6
ENST00000590449
ENST00000590449.1
ENST00000590925
ENST00000590925.6
ENST00000592734
ENST00000592734.5
EntrezGene:332
EntrezGene:BIRC5
g4502144_3p_a_at
g7416052_3p_a_at
g7416052_3p_x_at
GE59394
GO:0000228
GO:0000278
GO:0000775
GO:0000776
GO:0000777
GO:0003674
GO:0004869
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005819
GO:0005829
GO:0005856
GO:0005874
GO:0005876
GO:0006464
GO:0006468
GO:0006915
GO:0007010
GO:0007049
GO:0007059
GO:0007165
GO:0007605
GO:0008017
GO:0008092
GO:0008150
GO:0008219
GO:0008283
GO:0008284
GO:0008536
GO:0009058
GO:0010466
GO:0019221
GO:0019899
GO:0022607
GO:0030234
GO:0030414
GO:0030496
GO:0031503
GO:0032133
GO:0032991
GO:0034641
GO:0042802
GO:0042981
GO:0043027
GO:0043066
GO:0043154
GO:0043167
GO:0043226
GO:0045892
GO:0046872
GO:0050877
GO:0051087
GO:0051301
GO:0090307
GO:0140014
H3BLT4
HGNC:593
Hs.1578.0.S2_3p_at
ILMN_1710082
ILMN_1803124
ILMN_2349459
IPR001370
MIM:603352
NM_001012270
NP_001012270
PF00653
PH_hs_0000213
PH_hs_0040283
SM00238
UPI000006E9D2
UPI00002003CB
UPI000023FFA2
UPI000068F51E
XR_243654
Participant Of
hasComponent
hasMember
output
Other forms of this molecule
ub-BIRC5 [cytosol]
BIRC5 [cytosol]
Inferred To
Ghost homologue of BIRC5 [nucleoplasm] (Canis familiaris)
Ghost homologue of BIRC5 [nucleoplasm] (Drosophila melanogaster)
Ghost homologue of BIRC5 [nucleoplasm] (Rattus norvegicus)
Ghost homologue of BIRC5 [nucleoplasm] (Sus scrofa)
BIRC5 [nucleoplasm] (Danio rerio)
BIRC5 [nucleoplasm] (Mus musculus)
BIRC5 [nucleoplasm] (Schizosaccharomyces pombe)
BIRC5 [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
OpenTargets
GeneCards
ZINC - Substances
ZINC target
PRO
Orphanet
ZINC - Predictions - Purchasable
PDB
Interactors (18)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q96GD4 AURKB  3 0.954 13
 UniProt:Q53HL2 CDCA8  3 0.941 19
 UniProt:Q9NQS7 INCENP  2 0.891 10
 IntAct:EBI-15634422 H3K9-2      0.76 8
 UniProt:Q9UQB9 AURKC      0.739 10
 ChEBI:78766 LLP-3      0.65 4
 UniProt:P62826 RAN  2 0.645 7
 IntAct:EBI-15949926 HSGO1      0.618 3
 UniProt:O15392 BIRC5  3 0.609 2
 UniProt:P55211 CASP9  6 0.589 2
 UniProt:Q86XJ1 GA2L3      0.558 4
 IntAct:EBI-15963608 SMACN      0.558 2
 UniProt:O14965 AURKA  6 0.525 2
 UniProt:O14980 XPO1  2 0.524 2
 UniProt:Q14457 BECN1  3 0.524 3
 UniProt:A0A0C4DGV4 A0A0C4DGV4      0.488 2
 UniProt:Q15834 CC85B      0.488 2
 UniProt:P06493 CDK1  10 0.463 6