Reactome | MAGT1 [plasma membrane]

MAGT1 [plasma membrane]

Stable Identifier

R-HSA-4836523

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Magnesium transporter protein 1, MAGT1_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - SARS-CoV-2 Infection (Homo sapiens)
        
        Late SARS-CoV-2 Infection Events (Homo sapiens)
        
        Translation of Structural Proteins (Homo sapiens)
        
        Maturation of spike protein (Homo sapiens)
        
        Spike protein gets N-glycosylated (Homo sapiens)
        
        OST complex [endoplasmic reticulum membrane] (Homo sapiens)
        
        MAGT1 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9H0U3 MAGT1

Gene Names

MAGT1, IAG2, PSEC0084, UNQ628/PRO1244

Chain

signal peptide:1-29, chain:30-335

Reference Genes

BioGPS Gene:84061 MAGT1

COSMIC (genes):MAGT1 MAGT1

CTD Gene:84061 MAGT1

dbSNP Gene:84061 MAGT1

ENSEMBL:ENSG00000102158 MAGT1

ENSEMBL_homo_sapiens_GENE:ENSG00000102158.22 MAGT1

HGNC:28880 MAGT1

KEGG Gene (Homo sapiens):84061 MAGT1

Monarch:84061 MAGT1

NCBI Gene:84061 MAGT1

OMIM:300715 MAGT1

UCSC:Q9H0U3 MAGT1

Reference Transcript

RefSeq:NM_032121.5 MAGT1

Other Identifiers

11717899_x_at

11753222_s_at

11755486_s_at

11760041_at

17112316

221553_3p_at

221553_PM_at

221553_at

224899_PM_s_at

224899_s_at

4013361

4013362

4013363

4013364

4013365

4013366

4013367

4013368

4013369

4013370

4013371

4013372

4013375

4013376

4013379

4013380

4013382

4013383

4013386

4013390

4013391

4013392

4013393

4013403

4013405

4055286

4055407

4055408

4055409

4055410

4055411

4055422

4055423

4055424

4055425

4055428

4055429

4055439

43481_at

45230_at

8173713

84061

90925_at

A_23_P148273

A_24_P333802

A_24_P485219

A_33_P3240912

GE85351

GE86130

GO:0005215

GO:0005764

GO:0005773

GO:0005783

GO:0005789

GO:0005886

GO:0006486

GO:0006487

GO:0008250

GO:0015095

GO:0015693

GO:0016020

GO:0018279

GO:0031410

GO:0035577

GO:0036211

GO:0043226

GO:0050877

GO:0050890

GO:0055085

GO:1901135

GO:1903830

HMNXSV003053605

Hs.305979.1.S1_3p_at

PH_hs_0037858

PH_hs_0041084

TC0X001174.hg

g12052797_3p_x_at

Participates

as a member of

Azurophil granule membrane proteins [plasma membrane] (Homo sapiens)

as a component of

OST complex [endoplasmic reticulum membrane] (Homo sapiens)

Other forms of this molecule

MAGT1 [azurophil granule membrane]

Inferred To

Ostgamma [plasma membrane] (Drosophila melanogaster)

magt1 [plasma membrane] (Danio rerio)

Magt1 [plasma membrane] (Mus musculus)

Magt1 [plasma membrane] (Rattus norvegicus)

MAGT1 [plasma membrane] (Bos taurus)

MAGT1 [plasma membrane] (Caenorhabditis elegans)

MAGT1 [plasma membrane] (Canis familiaris)

MAGT1 [plasma membrane] (Gallus gallus)

MAGT1 [plasma membrane] (Plasmodium falciparum)

MAGT1 [plasma membrane] (Sus scrofa)

OST6 [plasma membrane] (Saccharomyces cerevisiae)

OST3 [plasma membrane] (Saccharomyces cerevisiae)

ost3 [plasma membrane] (Dictyostelium discoideum)

ost3 [plasma membrane] (Schizosaccharomyces pombe)

Homologues of MAGT1 [plasma membrane] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_115497.4

Guide to Pharmacology - Targets

3039

OpenTargets

ENSG00000102158

GeneCards

Q9H0U3

HPA

ENSG00000102158-MAGT1

Ensembl

ENST00000373336, ENSP00000362433, ENST00000618282, ENST00000358075, ENSG00000102158, ENSP00000354649, ENSP00000480732

PRO

Q9H0U3

Pharos - Targets

Q9H0U3

Orphanet

19585

HMDB Protein

HMDBP11812

PDB

6S7T

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96GX1 TCTN2	1	TCTN2 [ciliary membrane] (R-HSA-5626661)	0.619	4