YWHAB [cytosol]

Stable Identifier
R-HSA-48888
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
14-3-3 protein beta/alpha, 143B protein, Protein kinase C inhibitor protein-1, KCIP-1, Protein 1054
Icon
YWHAB [cytosol] icon
YWHAB [cytosol] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P31946 YWHAB
Gene Names
YWHAB
Chain
initiator methionine:1, chain:1-246, chain:2-246
Reference Genes
BioGPS Gene:7529 YWHAB
COSMIC (genes):YWHAB YWHAB
CTD Gene:7529 YWHAB
dbSNP Gene:7529 YWHAB
ENSEMBL:ENSG00000166913 YWHAB
ENSEMBL:ENSG00000166913.13 YWHAB
HGNC:12849 YWHAB
KEGG Gene (Homo sapiens):7529 YWHAB
Monarch:7529 YWHAB
NCBI Gene:7529 YWHAB
OMIM:601289 YWHAB
Reference Transcript
Other Identifiers
11725042_a_at
11725043_a_at
11725044_s_at
11731397_a_at
11757887_x_at
16914103
208743_PM_s_at
208743_s_at
217717_PM_s_at
217717_s_at
217718_PM_s_at
217718_s_at
32324_at
3886640
3886643
3886644
3886649
3886650
3886652
3886654
3886655
3886656
3886657
3886658
3886659
3886661
3886662
7529
8062880
A_23_P120414
GE81853
GO:0004860
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005773
GO:0005774
GO:0005829
GO:0005925
GO:0006605
GO:0006886
GO:0007165
GO:0016020
GO:0019899
GO:0019904
GO:0023052
GO:0031410
GO:0035308
GO:0036211
GO:0042470
GO:0042802
GO:0042826
GO:0043085
GO:0043226
GO:0045296
GO:0045744
GO:0048471
GO:0050815
GO:0051219
GO:0051220
GO:0070062
GO:0098772
HMNXSV003042369
Hs.182238.0.A1_3p_a_at
ILMN_1694385
ILMN_2277099
PH_hs_0023424
TC20000337.hg
X57346_at
g12655022_3p_s_at
g7661715_3p_a_at
Participates
as a component of
as an input of
as a member of
Inferred To
14-3-3zeta [cytosol] (Drosophila melanogaster)
par-5 [cytosol] (Caenorhabditis elegans)
ywhab [cytosol] (Xenopus tropicalis)
Ywhab [cytosol] (Rattus norvegicus)
ywhabb [cytosol] (Danio rerio)
14-3-3 beta/alpha [cytosol] (Mus musculus)
YWHAB [cytosol] (Bos taurus)
YWHAB [cytosol] (Caenorhabditis elegans)
YWHAB [cytosol] (Canis familiaris)
YWHAB [cytosol] (Gallus gallus)
YWHAB [cytosol] (Sus scrofa)
fttB [cytosol] (Dictyostelium discoideum)
Homologues of YWHAB [cytosol] (Caenorhabditis elegans)
ftt-2 [cytosol] (Caenorhabditis elegans)
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Pharos - Targets
HMDB Protein
PDB
Interactors (117)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P04049 RAF1  20 0.944 33
 UniProt:P49815 TSC2  4 0.93 11
 UniProt:P15056 BRAF  20 0.861 8
 UniProt:P30305 CDC25B  3 0.857 7
 UniProt:P08069 IGF1R  3 0.832 7
 UniProt:P27448 MARK3  1 0.822 7
 UniProt:P46937 YAP1  7 0.802 6
 UniProt:Q96TC7 RMD3      0.767 7
 UniProt:P62258 YWHAE  1 0.764 6
 UniProt:P26045 PTPN3  3 0.763 6
 UniProt:Q9Y2J2 EPB41L3  1 0.758 4
 UniProt:Q9Y2U5 M3K2      0.758 4
 UniProt:Q5S007 LRRK2  1 0.75 5
 UniProt:O96013 PAK4  1 0.744 5
 UniProt:P30307 CDC25C  8 0.744 5
 UniProt:P30291 WEE1  3 0.736 4
 UniProt:P10398 ARAF  4 0.725 7
 UniProt:Q02750 MAP2K1  20 0.725 5
 UniProt:Q04917 YWHAH  1 0.725 4
 UniProt:P22893  2 0.725 5
 UniProt:P63104 YWHAZ  2 0.725 5
 UniProt:P30304 CDC25A  6 0.701 10
 UniProt:Q16890 TPD52L1  2 0.691 4
 UniProt:Q9Y2A7 NCKAP1  1 0.688 3
 UniProt:Q96F86 EDC3  1 0.688 4
 UniProt:Q6ICG6 K0930      0.688 3
 UniProt:Q7Z401 DENND4A  1 0.688 4
 UniProt:Q14C86 GAPVD1  1 0.688 3
 UniProt:Q86X27 RGPS2      0.688 4
 UniProt:Q12802 AKAP13  1 0.688 3
 UniProt:Q8TEW0 PARD3  3 0.688 3
 UniProt:Q96NE9 FRMD6      0.688 3
 UniProt:P61981 YWHAG  1 0.688 3
 UniProt:Q9Y4H2 IRS2  4 0.688 3
 UniProt:P27348 YWHAQ  1 0.688 3
 UniProt:Q6PKG0 LARP1  1 0.688 4
 UniProt:P40818 USP8  2 0.688 4
 UniProt:Q02241 KIF23  3 0.688 3
 UniProt:Q9UBF8 PI4KB  2 0.688 4
 UniProt:P19634 SLC9A1  1 0.678 4
 UniProt:O14649 KCNK3  1 0.67 5
 UniProt:Q5TCX8 M3K21      0.669 3
 UniProt:Q7KZI7 MARK2      0.669 4
 UniProt:Q53ET0 CRTC2  1 0.669 3
 UniProt:P31946 YWHAB  1 0.667 3
 UniProt:P54253 ATX1      0.666 4
 UniProt:P42858 HTT  1 0.666 11
 UniProt:Q92934 BAD  4 0.659 4
 UniProt:P56524 HDAC4  3 0.643 3
 UniProt:P36507 MAP2K2  12 0.643 4
 UniProt:P22681 CBL  20 0.643 3
 UniProt:Q51451 Q51451      0.637 3
 UniProt:Q61097  5 0.632 3
 UniProt:Q99683 MAP3K5  1 0.632 3
 UniProt:Q15569 TESK1  1 0.611 4
 UniProt:P55040 GEM  1 0.597 4
 UniProt:P78362 SRPK2  1 0.59 2
 UniProt:Q96JH8 RADIL      0.589 2
 UniProt:Q9UJ41 RABGEF1  2 0.589 2
 UniProt:Q9UDY2 TJP2  4 0.589 2
 UniProt:P68400 CSNK2A1  2 0.589 2
 UniProt:Q96SB4 SRPK1  2 0.589 2
 UniProt:O94915 FRYL      0.589 2
 UniProt:Q9UKV3 ACIN1  4 0.589 2
 UniProt:Q8N3F8 MILK1      0.589 2
 UniProt:Q96Q42 ALS2  1 0.589 2
 UniProt:Q86X29 LSR  1 0.589 2
 UniProt:Q9Y6M7 SLC4A7  1 0.589 2
 UniProt:Q07866 KLC1  3 0.589 2
 UniProt:Q9H4L5 OSBPL3  1 0.589 2
 UniProt:O75592 MYCB2      0.589 2
 UniProt:Q99570 PIK3R4  2 0.589 2
 UniProt:Q9UQ35 SRRM2  1 0.589 2
 UniProt:P33176 KIF5B  3 0.589 2
 UniProt:Q6WCQ1 MPRIP  2 0.589 2
 UniProt:O75643 SNRNP200  1 0.589 2
 UniProt:Q9P0K7 RAI14      0.589 2
 UniProt:Q9H0H5 RACGAP1  1 0.589 2
 UniProt:O94921 CDK14      0.581 5
 UniProt:Q9NYF0 DACT1  1 0.581 4
 UniProt:P67828 KC1A      0.576 3
 UniProt:P61588  1 0.576 5
 UniProt:Q9NSK0 KLC4  1 0.564 2
 UniProt:Q92538 GBF1  2 0.564 2
 UniProt:Q99759 MAP3K3  1 0.564 2
 UniProt:Q5PRF9 SMAG2      0.564 2
 UniProt:Q86W92 PPFIBP1  5 0.564 2
 UniProt:Q9UQC2 GAB2  5 0.558 4
 UniProt:Q76353 Q76353      0.558 3
 UniProt:A0A0S2Z5Q7 A0A0S2Z5Q7      0.556 3
 UniProt:P05067 APP  20 0.556 3
 UniProt:P00533 EGFR  20 0.553 2
 UniProt:P07228 ITGB1  1 0.543 3
 UniProt:Q6R327 RICTOR  1 0.527 2
 UniProt:Q6VAB6 KSR2  1 0.527 6
 UniProt:P55041 GEM      0.527 3
 UniProt:Q91YE8 SYNP2      0.527 3
 UniProt:Q8WUI4 HDAC7  1 0.527 3
 UniProt:P00519 ABL1  5 0.527 2
 UniProt:B7UM99 TIR      0.527 2
 UniProt:Q8N5S9 CAMKK1  4 0.527 2
 UniProt:O14654 IRS4  2 0.527 2
 UniProt:Q8WYL5 SSH1      0.527 3
 UniProt:Q13470 TNK1      0.527 2
 UniProt:Q9UQL6 HDAC5  1 0.527 2
 UniProt:Q9ULR3 PPM1H      0.527 2
 UniProt:Q00536 CDK16      0.527 2
 UniProt:Q96B36 AKT1S1  4 0.527 2
 UniProt:P19320 VCAM1  1 0.527 4
 UniProt:P62993 GRB2  1 0.527 3
 UniProt:O43524 FOXO3  9 0.527 3
 UniProt:P55957 BID  4 0.524 2
 UniProt:Q13627-2 DYRK1A      0.508 3
 UniProt:Q11184  19 0.508 2
 UniProt:Q9P0K1-3 ADAM22      0.508 2
 UniProt:O00257 CBX4  2 0.499 2
 UniProt:P13569 CFTR  17 0.483 7
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