Activation of GRIK3 homomer

Stable Identifier
R-HSA-500717
Type
Reaction [transition]
Species
Homo sapiens
Compartment
extracellular region, plasma membrane, cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Activation of GRIK3 homomer
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Kainate receptor activation activates G protein coupled receptors involving the release of Ca2+ from the intracellular stores. This activity of Kainate receptors is independent of ionic influx and regulates both glutamate release by the pyramidal neurons and gama-aminobutyric acid release by the internuerons.
Literature References
PubMed ID Title Journal Year
20007474 Atypical functional properties of GluK3-containing kainate receptors

Coussen, F, Perrais, D, Mulle, C

J Neurosci 2009
Participants
Input
Output
Participates
as an event of
Catalyst Activity

G protein-coupled receptor binding activity of GRIK3 homomer glutamate complex [plasma membrane]

Physical Entity
GRIK3 homomer glutamate complex [plasma membrane] (Homo sapiens)
Activity
G protein-coupled receptor binding (GO:0001664)
Orthologous Events
Activation of GRIK3 homomer (Bos taurus)
Activation of GRIK3 homomer (Canis familiaris)
Activation of GRIK3 homomer (Drosophila melanogaster)
Activation of GRIK3 homomer (Gallus gallus)
Activation of GRIK3 homomer (Mus musculus)
Activation of GRIK3 homomer (Sus scrofa)
Activation of GRIK3 homomer (Xenopus tropicalis)
Authored
Mahajan, SS  (2010-02-05)
Reviewed
Tukey, D  (2009-11-18)
Created
Mahajan, SS  (2010-02-05)
Cite Us!