Reactome | ATP5J2 [mitochondrial inner membrane]

ATP5J2 [mitochondrial inner membrane]

Stable Identifier

R-HSA-50516

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

ATP synthase f chain, mitochondrial (EC 3.6.3.14)

Locations in the PathwayBrowser

Expand all

Organelle biogenesis and maintenance (Homo sapiens)

- Mitochondrial biogenesis (Homo sapiens)
  - Cristae formation (Homo sapiens)
    - F1Fo ATP synthase dimerizes (Homo sapiens)
      - F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5J2 [mitochondrial inner membrane] (Homo sapiens)
      - F1Fo ATP synthase dimer [mitochondrial inner membrane] (Homo sapiens)
        
        F1Fo ATP synthase [mitochondrial inner membrane] (Homo sapiens)
        
        ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)
        
        ATP5J2 [mitochondrial inner membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:P56134 ATP5MF

Gene Names

ATP5MF, ATP5J2, ATP5JL

Chain

initiator methionine:, chain:2-94

Reference Genes

BioGPS Gene:9551 ATP5MF

COSMIC (genes):ATP5MF ATP5MF

CTD Gene:9551 ATP5MF

dbSNP Gene:9551 ATP5MF

ENSEMBL:ENSG00000241468 ATP5J2

ENSEMBL_homo_sapiens_GENE:ENSG00000241468.8 ATP5MF

HGNC:848 ATP5MF

KEGG Gene (Homo sapiens):9551 ATP5MF

Monarch:9551 ATP5MF

NCBI Gene:9551 ATP5MF

OMIM:619792 ATP5MF

UCSC:P56134 ATP5MF

Reference Transcript

Other Identifiers

11725612_x_at

11743715_x_at

11754002_s_at

11754003_x_at

17060237

202961_PM_s_at

202961_s_at

3063306

3063307

3063308

3063309

3063312

3063314

3063320

40134_at

8141295

9551

A_24_P343377

GE54407

GO:0003824

GO:0005215

GO:0005634

GO:0005635

GO:0005739

GO:0005743

GO:0005753

GO:0006091

GO:0006754

GO:0006811

GO:0015986

GO:0016020

GO:0016874

GO:0031965

GO:0042776

GO:0043226

GO:0045263

GO:0046933

GO:0055085

GO:0055086

GO:1901135

GO:1902600

HMNXSV003056984

Hs2.376369.1.S1_3p_s_at

ILMN_2307883

ILMN_2310621

PH_hs_0012820

Participates

as a component of

ATPase CF(0) [mitochondrial inner membrane] (Homo sapiens)

Inferred To

ATP5MF [mitochondrial inner membrane] (Bos taurus)

ATP5MF [mitochondrial inner membrane] (Sus scrofa)

Atp5mf [mitochondrial inner membrane] (Mus musculus)

Atp5mf [mitochondrial inner membrane] (Rattus norvegicus)

Ghost homologue of ATP5J2 [mitochondrial inner membrane] (Danio rerio)

Ghost homologue of ATP5J2 [mitochondrial inner membrane] (Saccharomyces cerevisiae)

ATPsynF [mitochondrial inner membrane] (Drosophila melanogaster)

ATP5J2 [mitochondrial inner membrane] (Caenorhabditis elegans)

ATP5J2 [mitochondrial inner membrane] (Canis familiaris)

ATP5J2 [mitochondrial inner membrane] (Gallus gallus)

Cross References

RefSeq

NP_001003714.1, NP_004880.1, NP_001034267.1, NP_001003713.1

Guide to Pharmacology - Targets

806

OpenTargets

ENSG00000241468

HPA

ENSG00000241468-ATP5MF

GeneCards

P56134

Ensembl

ENST00000292475, ENST00000359832, ENSP00000412149, ENST00000488775, ENSP00000377740, ENST00000414062, ENST00000394186, ENSG00000241468, ENSP00000292475, ENSP00000418197, ENSP00000352890

PRO

P56134

Pharos - Targets

P56134

HMDB Protein

HMDBP01532

PDB

8H9S, 8H9T, 8H9Q, 8H9F, 8H9M, 8H9U, 8H9J, 8H9V

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P01106 MYC	2	PolyUb-MYC [nucleoplasm] (R-HSA-6783169) MYC [nucleoplasm] (R-HSA-188379)	0.527	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	12