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MLST8:MTOR:RPTOR:AKT1S1 [nucleoplasm]
Stable Identifier
R-HSA-5083661
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
mTORC1
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to heat stress (Homo sapiens)
HSF1-dependent transactivation (Homo sapiens)
Phosphorylation of HSF1 at Ser326 induces transactivation (Homo sapiens)
mTORC1 dimer [nucleoplasm] (Homo sapiens)
MLST8:MTOR:RPTOR:AKT1S1 [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
20542007
Structure of the human mTOR complex I and its implications for rapamycin inhibition
Yip, CK
,
Sabatini, DM
,
Kang, SA
,
Walz, T
,
Murata, K
Mol. Cell
2010
Participants
components
AKT1S1 [nucleoplasm]
(Homo sapiens)
MLST8 [nucleoplasm]
(Homo sapiens)
MTOR [nucleoplasm]
(Homo sapiens)
RPTOR [nucleoplasm]
(Homo sapiens)
Participates
as a component of
mTORC1 dimer [nucleoplasm] (Homo sapiens)
Inferred To
MLST8:MTOR:RPTOR:AKT1S1 [nucleoplasm]
(Bos taurus)
MLST8:MTOR:RPTOR:AKT1S1 [nucleoplasm]
(Caenorhabditis elegans)
MLST8:MTOR:RPTOR:AKT1S1 [nucleoplasm]
(Canis familiaris)
MLST8:MTOR:RPTOR:AKT1S1 [nucleoplasm]
(Dictyostelium discoideum)
MLST8:MTOR:RPTOR:AKT1S1 [nucleoplasm]
(Drosophila melanogaster)
MLST8:MTOR:RPTOR:AKT1S1 [nucleoplasm]
(Gallus gallus)
MLST8:MTOR:RPTOR:AKT1S1 [nucleoplasm]
(Mus musculus)
MLST8:MTOR:RPTOR:AKT1S1 [nucleoplasm]
(Rattus norvegicus)
MLST8:MTOR:RPTOR:AKT1S1 [nucleoplasm]
(Saccharomyces cerevisiae)
MLST8:MTOR:RPTOR:AKT1S1 [nucleoplasm]
(Schizosaccharomyces pombe)
MLST8:MTOR:RPTOR:AKT1S1 [nucleoplasm]
(Sus scrofa)
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