BIRC3 [cytosol]

Stable Identifier
R-HSA-50845
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
C-IAP2, Baculoviral IAP repeat-containing protein 2 (Inhibitor of apoptosis protein 1) (HIAP1) (HIAP-1) (C-IAP2) (TNFR2-TRAF signaling complex protein 1) (IAP homolog C), Baculoviral IAP repeat-containing protein 3, Inhibitor of apoptosis protein 1, HIAP1, HIAP-1, TNFR2-TRAF signaling complex protein 1, IAP homolog C, Apoptosis inhibitor 2, API2
Icon
BIRC3 [cytosol] icon
BIRC3 [cytosol] icon
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:Q13489 BIRC3
Gene Names
BIRC3, API2, MIHC, RNF49
Chain
chain:1-604
Reference Genes
BioGPS Gene:330 BIRC3
COSMIC (genes):BIRC3 BIRC3
CTD Gene:330 BIRC3
dbSNP Gene:330 BIRC3
ENSEMBL:ENSG00000023445 BIRC3
HGNC:591 BIRC3
KEGG Gene (Homo sapiens):330 BIRC3
Monarch:330 BIRC3
NCBI Gene:330 BIRC3
OMIM:601721 BIRC3
UCSC:Q13489 BIRC3
Reference Transcript
Other Identifiers
0004670717
0006840673
11722850_a_at
11722851_at
11722852_s_at
16730522
1717_s_at
210538_s_at
230499_at
2317
2UVL
330
3346545
3346546
3346547
3346549
3346553
3346554
3346555
3346556
3346558
3346560
3346561
3346563
3346564
3346566
3346567
3346569
3346570
3346571
3346572
3346573
3346574
3346575
3346576
3346577
3346578
3346580
3346581
3EB5
3EB6
3M0A
3M0D
63769_at
7943413
88714_at
91017_at
A_14_P125254
A_23_P98350
AAC41943
AAC50371
AAC50507
AAC83232
AAG09369
AAH37420
AAU88144
AF070674
AF178945
AY764389
BC037420
BIRC3
BIRC3-201
BIRC3-206
BIRC3-207
CCDS8315
ENSG00000023445
ENSP00000263464
ENSP00000432907
ENSP00000481903
ENST00000263464
ENST00000263464.7
ENST00000532808
ENST00000532808.5
ENST00000615299
ENST00000615299.4
EntrezGene:330
EntrezGene:BIRC3
g1145290_3p_a_at
GE58248
GO:0000003
GO:0002376
GO:0002756
GO:0003674
GO:0004842
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006464
GO:0006915
GO:0006950
GO:0007165
GO:0007166
GO:0007249
GO:0007283
GO:0008150
GO:0008219
GO:0010803
GO:0016567
GO:0016579
GO:0016740
GO:0022607
GO:0030234
GO:0031398
GO:0032991
GO:0033209
GO:0034121
GO:0035666
GO:0038061
GO:0039535
GO:0042981
GO:0043027
GO:0043066
GO:0043123
GO:0043154
GO:0043167
GO:0043226
GO:0044877
GO:0045088
GO:0045121
GO:0046872
GO:0050727
GO:0051291
GO:0051604
GO:0060544
GO:0060546
GO:0061630
GO:0065003
GO:0070424
GO:1990001
GO:2000116
H0YCJ5
HGNC:591
HPA002317
Hs.121572.0.A1_3p_at
ILMN_1681644
ILMN_1696549
ILMN_1776181
ILMN_2405684
IPR001315
IPR001370
IPR001841
IPR011029
L49432
MIM:601721
NM_001165
NM_182962
NP_001156
NP_892007
PF00619
PF00653
PF13920
PH_hs_0007351
SM00114
SM00184
SM00238
TC11000956.hg
U37546
U37546_s_at
U45878
U45878_s_at
UPI0000001C60
XM_024448467
XP_024304235
Participant Of
hasMember
hasComponent
hasCandidate
Other forms of this molecule
K48pUb-BIRC3 [cytosol]
K63polyUb-BIRC3 [cytosol]
Inferred To
Diap2 [cytosol] (Drosophila melanogaster)
Birc3 [cytosol] (Mus musculus)
Birc3 [cytosol] (Rattus norvegicus)
BIRC3 [cytosol] (Bos taurus)
BIRC3 [cytosol] (Canis familiaris)
BIRC3 [cytosol] (Gallus gallus)
BIRC3 [cytosol] (Sus scrofa)
Diap1 [cytosol] (Drosophila melanogaster)
birc2 [cytosol] (Danio rerio)
birc2 [cytosol] (Xenopus tropicalis)
Homologues of BIRC3 [cytosol] (Drosophila melanogaster)
bir1 [cytosol] (Schizosaccharomyces pombe)
Cross References
RefSeq
OpenTargets
ZINC - Substances
ZINC target
PRO
PDB
ZINC - Investigational
IntEnz
HPA
GeneCards
Ensembl
ZINC - Predictions - Purchasable
Orphanet
Interactors (9)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q12933 TRAF2  5 0.842 7
 UniProt:Q13546 RIPK1  9 0.602 3
 UniProt:Q9Y572 RIPK3  2 0.602 3
 UniProt:O43353 RIPK2  2 0.602 3
 UniProt:P61088 UBE2N  5 0.592 2
 UniProt:P22314 UBA1  2 0.59 2
 UniProt:P55211 CASP9  6 0.573 2
 UniProt:Q9NR28 DIABLO  2 0.564 2
 UniProt:Q13077 TRAF1  3 0.564 2