Reactome | FZD2 [clathrin-coated endocytic vesicle membrane]

FZD2 [clathrin-coated endocytic vesicle membrane]

Stable Identifier

R-HSA-5140723

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

clathrin-coated endocytic vesicle membrane

Synonyms

Frizzled-2, FZD2_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q14332 FZD2

Gene Names

FZD2

Chain

signal peptide:1-23, chain:24-565

Reference Genes

BioGPS Gene:2535 FZD2

COSMIC (genes):FZD2 FZD2

CTD Gene:2535 FZD2

dbSNP Gene:2535 FZD2

ENSEMBL:ENSG00000180340 FZD2

HGNC:4040 FZD2

KEGG Gene (Homo sapiens):2535 FZD2

Monarch:2535 FZD2

NCBI Gene:2535 FZD2

OMIM:600667 FZD2

UCSC:Q14332 FZD2

Reference Transcript

RefSeq:NM_001466.3 FZD2

Other Identifiers

0002030592

11727552_at

16834785

210220_at

238129_s_at

2535

36799_at

3723009

3723010

3723011

3723012

3723013

3723014

3723015

3723016

3723017

3723018

46871_r_at

61063_at

628_at

8007637

A_14_P126073

A_23_P141362

GE58254

GO:0003149

GO:0003150

GO:0003151

GO:0003674

GO:0004888

GO:0004930

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005886

GO:0005925

GO:0007165

GO:0007166

GO:0007186

GO:0007223

GO:0007267

GO:0007275

GO:0007608

GO:0008150

GO:0009058

GO:0009790

GO:0016020

GO:0016021

GO:0016055

GO:0017147

GO:0030154

GO:0030165

GO:0030182

GO:0030669

GO:0030855

GO:0031410

GO:0034641

GO:0042813

GO:0043226

GO:0045893

GO:0048646

GO:0048856

GO:0050877

GO:0051091

GO:0060022

GO:0060070

GO:0060071

GO:0060119

GO:0060412

GO:0090103

GO:0090179

GO:1904886

HMNXSV003007369

Hs.142912.0.A1_3p_at

ILMN_1653711

L37882_at

PH_hs_0031791

TC17000571.hg

g736678_3p_at

Participates

as a member of

FZD2/FZD5/ROR2 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)

Other forms of this molecule

FZD2 [plasma membrane]

Inferred To

Fzd2 [clathrin-coated endocytic vesicle membrane] (Mus musculus)

Fzd2 [clathrin-coated endocytic vesicle membrane] (Rattus norvegicus)

mom-5 [clathrin-coated endocytic vesicle membrane] (Caenorhabditis elegans)

fzd2 [clathrin-coated endocytic vesicle membrane] (Danio rerio)

fz [clathrin-coated endocytic vesicle membrane] (Drosophila melanogaster)

FZD2 [clathrin-coated endocytic vesicle membrane] (Bos taurus)

FZD2 [clathrin-coated endocytic vesicle membrane] (Canis familiaris)

FZD2 [clathrin-coated endocytic vesicle membrane] (Gallus gallus)

FZD2 [clathrin-coated endocytic vesicle membrane] (Sus scrofa)

Cross References

RefSeq

NP_001457.1

OpenTargets

ENSG00000180340

HPA

ENSG00000180340-FZD2

GeneCards

Q14332

Ensembl

ENSP00000323901, ENST00000315323, ENSG00000180340

PRO

Q14332

Orphanet

23281

PDB

6C0B

HMDB Protein

HMDBP07698

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P39688 Fyn	6	Fyn [cytosol] (R-MMU-420333) phospho-Fyn [plasma membrane] (R-MMU-9032530) pFyn (420) [cytosol] (R-MMU-420335) pFyn(Y531) [cytosol] (R-MMU-420350) phospho-Fyn [cytosol] (R-MMU-5218745) MyrG,p-Y420-Fyn [plasma membrane] (R-MMU-9037733)	0.525	4