Reactome: A Curated Pathway Database

WNT5A-dependent internalization of FZD2, FZD5 and ROR2

Stable Identifier
R-HSA-5140745
Type
Pathway
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Internalization of FZD2, FZD5 and ROR2 after WNT5A binding is thought to occur in a clathrin-dependent manner and is required for the activation of RAC signaling (Kurayoshi et al, 2007; Sato et al, 2010; Hanaki et al, 2012; Yamamoto et al, 2009).

Literature References
Participants
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Orthologous Events