Reactome | NCBP2 [nucleoplasm]

NCBP2 [nucleoplasm]

Stable Identifier

R-HSA-51463

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

CBP20, 20 kDa nuclear cap binding protein (NCBP 20 kDa subunit) (CBP20) (NCBP interacting protein 1) (NIP1), 20 kDa nuclear cap binding protein, NCBP 20 kDa subunit, NCBP interacting protein 1, NIP1

Icon

Locations in the PathwayBrowser for interactor UniProt:Q9Y580 RBM7

Expand all

External Reference Information

External Reference

UniProt:P52298 NCBP2

Gene Names

NCBP2, CBP20, PIG55

Chain

initiator methionine:, chain:2-156

Reference Genes

BioGPS Gene:22916 NCBP2

COSMIC (genes):NCBP2 NCBP2

CTD Gene:22916 NCBP2

dbSNP Gene:22916 NCBP2

ENSEMBL:ENSG00000114503 NCBP2

HGNC:7659 NCBP2

KEGG:hsa:22916 NCBP2

Monarch:22916 NCBP2

NCBI Gene:22916 NCBP2

OMIM:605133 NCBP2

UCSC:P52298 NCBP2

Reference Transcript

Participates

as a component of

as an output of

Docking of Mature Replication Dependent Histone mRNA with the NPC (Homo sapiens)

as an input of

Formation of cap binding complex (CBC) (Homo sapiens)

Other forms of this molecule

NCBP2 [cytosol]

Inferred To

NCBP2 [nucleoplasm] (Bos taurus)

NCBP2 [nucleoplasm] (Caenorhabditis elegans)

NCBP2 [nucleoplasm] (Canis familiaris)

NCBP2 [nucleoplasm] (Danio rerio)

NCBP2 [nucleoplasm] (Dictyostelium discoideum)

NCBP2 [nucleoplasm] (Drosophila melanogaster)

NCBP2 [nucleoplasm] (Gallus gallus)

NCBP2 [nucleoplasm] (Mus musculus)

NCBP2 [nucleoplasm] (Plasmodium falciparum)

NCBP2 [nucleoplasm] (Rattus norvegicus)

NCBP2 [nucleoplasm] (Saccharomyces cerevisiae)

NCBP2 [nucleoplasm] (Schizosaccharomyces pombe)

NCBP2 [nucleoplasm] (Sus scrofa)

NCBP2 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_001036005.1, NP_031388.2, NP_001294965.1

OpenTargets

ENSG00000114503

ENSEMBL

ENSG00000114503, ENSP00000326806, ENST00000321256, ENSP00000397619, ENST00000452404, ENSP00000412785, ENST00000427641

HPA

ENSG00000114503-NCBP2

GeneCards

NCBP2

PRO

P52298

Pharos - Targets

P52298

GlyGen

P52298

PDB

5OOB, 8PMP, 8SRR, 6D0Y, 8PNT, 5OO6, 8SUY, 7ABG, 1H2T, 1N52, 1N54, 1H2V, 1H2U, 3FEY, 3FEX, 8BY6, 1H6K

Interactors (25)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q09161 NCBP1	2	NCBP1 [nucleoplasm] (R-HSA-51469) NCBP1 [cytosol] (R-HSA-162459)	0.965	54
UniProt:Q9H814 PHAX	2	PHAX [cytosol] (R-HSA-191804) PHAX [nucleoplasm] (R-HSA-191803)	0.725	10
ChEBI:50210 7-METHYL-GTP			0.688	13
UniProt:Q86VM9 ZC3H18	1	ZC3H18 [nucleoplasm] (R-HSA-9930040)	0.643	6
UniProt:Q9BXP5 SRRT	1	SRRT [nucleoplasm] (R-HSA-6814858)	0.643	8
UniProt:P52294 KPNA1	2	KPNA1 [cytosol] (R-HSA-180612) KPNA1 [nucleoplasm] (R-HSA-188865)	0.643	3
UniProt:O00505 KPNA3	2	KPNA3 [nucleoplasm] (R-HSA-1176061) KPNA3 [cytosol] (R-HSA-1176070)	0.643	9
UniProt:P18615 NELFE	2	NELFE [nucleoplasm] (R-HSA-62907) p-NELFE [nucleoplasm] (R-HSA-170698)	0.643	4
UniProt:Q6NZY4 ZCCHC8	1	ZCCHC8 [nucleoplasm] (R-HSA-8985573)	0.643	3
UniProt:P52292 KPNA2	2	KPNA2 [cytosol] (R-HSA-205976) KPNA2 [nucleoplasm] (R-HSA-206045)	0.643	6
UniProt:Q9Y5S9 RBM8A	2	RBM8A [nucleoplasm] (R-HSA-156659) RBM8A [cytosol] (R-HSA-162462)	0.643	3
UniProt:Q9BRK4 LZTS2			0.556	3
UniProt:P42285 SKIV2L2	2	SKIV2L2 [nucleoplasm] (R-HSA-6791189) MTREX [nucleolus] (R-HSA-9935826)	0.527	4
UniProt:O60684 KPNA6	2	KPNA6 [nucleoplasm] (R-HSA-9734665) KPNA6 [cytosol] (R-HSA-9734672)	0.527	2
UniProt:Q9NR30 DDX21	1	DDX21 [nucleoplasm] (R-HSA-5250652)	0.527	2
UniProt:Q53F19 NCBP3			0.527	4
UniProt:O00629 KPNA4	2	KPNA4 [cytosol] (R-HSA-1176066) KPNA4 [nucleoplasm] (R-HSA-1176058)	0.527	2
UniProt:Q9Y580 RBM7	1	RBM7 [nucleoplasm] (R-HSA-8985564)	0.527	2
UniProt:P14678 SNRPB	4	2xMe-SNRPB [cytosol] (R-HSA-192218) SNRPB [cytosol] (R-HSA-191798) Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213) SNRPB [nucleoplasm] (R-HSA-71896)	0.527	2
UniProt:Q92900 UPF1	2	UPF1 [cytosol] (R-HSA-927734) p-4S-UPF1 [cytosol] (R-HSA-927856)	0.527	3
UniProt:P38919 EIF4A3	2	EIF4A3 [nucleoplasm] (R-HSA-8849149) EIF4A3 [cytosol] (R-HSA-927868)	0.527	5
UniProt:Q8WX92 NELFB	3	NELFB [cytosol] (R-HSA-9603526) NELFB [mitochondrial outer membrane] (R-HSA-9603553) NELFB [nucleoplasm] (R-HSA-112427)	0.527	3
UniProt:P09012 SNRPA	1	SNRPA [nucleoplasm] (R-HSA-71915)	0.527	2
UniProt:P27824 CANX	2	CANX [endoplasmic reticulum lumen] (R-HSA-195906) CANX [lumenal side of endoplasmic reticulum membrane] (R-HSA-983091)	0.483	2
UniProt:Q9NWB6 ARGL1			0.483	2

Cite Us!