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CCNT1 [nucleoplasm]
Stable Identifier
R-HSA-51611
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Cyclin T1, Cyclin T, CycT1
Locations in the PathwayBrowser for interactor UniProt:P50750
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
Host Interactions of HIV factors (Homo sapiens)
Interactions of Tat with host cellular proteins (Homo sapiens)
Formation of the P-TEFb(Cyclin T1:Cdk9) complex (Homo sapiens)
CCNT1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60563 CCNT1
Gene Names
CCNT1
Chain
chain:1-726
Reference Genes
BioGPS Gene:904 CCNT1
COSMIC (genes):CCNT1 CCNT1
CTD Gene:904 CCNT1
dbSNP Gene:904 CCNT1
ENSEMBL:ENSG00000129315 CCNT1
ENSEMBL_homo_sapiens_GENE:ENSG00000129315.12 CCNT1
HGNC:1599 CCNT1
KEGG Gene (Homo sapiens):904 CCNT1
Monarch:904 CCNT1
NCBI Gene:904 CCNT1
OMIM:143055 CCNT1
UCSC:O60563 CCNT1
Reference Transcript
RefSeq:NM_001277842.1 CCNT1
RefSeq:NM_001240.3 CCNT1
Other Identifiers
11740231_a_at
16763970
206967_PM_at
206967_at
225493_PM_at
225493_at
3453215
3453216
3453217
3453219
3453220
3453222
3453225
3453226
3453227
3453229
3453230
3453233
3453234
3453237
3453238
3453242
3453243
36391_at
3720861
44701_at
7962831
904
A_23_P87575
A_23_P98963
A_24_P136415
GE56015
GE62659
GO:0000079
GO:0000307
GO:0000976
GO:0003677
GO:0003682
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0007049
GO:0008024
GO:0009410
GO:0016538
GO:0017069
GO:0019901
GO:0032786
GO:0032968
GO:0036211
GO:0043226
GO:0043923
GO:0045944
GO:0051301
GO:0060090
GO:0061575
GO:0070063
GO:0070691
GO:0097322
GO:0098772
GO:0140297
GO:0140693
HMNXSV003021496
Hs.92308.0.S1_3p_at
ILMN_1692390
ILMN_1817255
PH_hs_0005116
PH_hs_0014426
TC12001456.hg
TC12002862.hg
g4502626_3p_at
Participates
as an input of
Formation of the P-TEFb(Cyclin T1:Cdk9) complex (Homo sapiens)
as a component of
P-TEFb(Cyclin T1:Cdk9) complex [nucleoplasm] (Homo sapiens)
as a member of
CCNT1,CCNT2,CCNK [nucleoplasm] (Homo sapiens)
Inferred To
lsc1 [nucleoplasm]
(Schizosaccharomyces pombe)
Ccnt1 [nucleoplasm]
(Mus musculus)
Ccnt1 [nucleoplasm]
(Rattus norvegicus)
Ghost homologue of CCNT1 [nucleoplasm]
(Plasmodium falciparum)
Ghost homologue of CCNT1 [nucleoplasm]
(Xenopus tropicalis)
cit-1.2 [nucleoplasm]
(Caenorhabditis elegans)
pch1 [nucleoplasm]
(Schizosaccharomyces pombe)
CCNT1 [nucleoplasm]
(Bos taurus)
CCNT1 [nucleoplasm]
(Canis familiaris)
CCNT1 [nucleoplasm]
(Gallus gallus)
CCNT1 [nucleoplasm]
(Sus scrofa)
cit-1.1 [nucleoplasm]
(Caenorhabditis elegans)
BUR2 [nucleoplasm]
(Saccharomyces cerevisiae)
cycK [nucleoplasm]
(Dictyostelium discoideum)
CTK2 [nucleoplasm]
(Saccharomyces cerevisiae)
CycT [nucleoplasm]
(Drosophila melanogaster)
Homologues of CCNT1 [nucleoplasm]
(Caenorhabditis elegans)
Homologues of CCNT1 [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of CCNT1 [nucleoplasm]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_001231.2
,
NP_001264771.1
OpenTargets
ENSG00000129315
HPA
ENSG00000129315-CCNT1
GeneCards
O60563
ZINC - Substances
CCNT1_HUMAN
ZINC target
O60563
Ensembl
ENSP00000261900
,
ENST00000417344
,
ENSP00000399845
,
ENSP00000481035
,
ENSG00000129315
,
ENST00000618666
,
ENST00000261900
PRO
O60563
Pharos - Targets
O60563
ZINC - Predictions - Purchasable
CCNT1_HUMAN
PDB
4BCJ
,
3MY1
,
3TN8
,
6Z45
,
4BCI
,
3LQ5
,
4OGR
,
5L1Z
,
4EC8
,
4BCH
,
6CYT
,
4OR5
,
3BLR
,
4IMY
,
7NWK
,
4BCG
,
3TNI
,
3BLQ
,
6W9E
,
3BLH
,
3TNH
,
3MIA
,
4BCF
,
6GZH
,
4EC9
,
2PK2
,
3MI9
Interactors (14)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P50750 CDK9
1
CDK9 [nucleoplasm]
(R-HSA-51801)
0.976
27
UniProt:O94992 HEXI1
0.872
10
UniProt:P04608 tat
1
Tat (P04608) [nucleoplasm]
(R-HIV-175856)
0.78
9
UniProt:Q9UHB7 AFF4
1
AFF4 [nucleoplasm]
(R-HSA-8932788)
0.758
6
UniProt:Q4G0J3 LARP7
0.597
4
UniProt:O60885-1 BRD4
0.544
6
UniProt:O12161 MINT-5231871
0.544
2
UniProt:P04326 TAT
0.536
2
UniProt:P51825 AFF1
0.532
8
IntAct:EBI-2890930 MLL
0.527
2
UniProt:P48426 PIP4K2A
2
PIP4K2A [nucleoplasm]
(R-HSA-6811484)
PIP4K2A [cytosol]
(R-HSA-1604641)
0.527
2
UniProt:Q6PD62 CTR9
1
CTR9 [nucleoplasm]
(R-HSA-8866694)
0.527
2
UniProt:P04610 TAT
0.499
2
UniProt:Q6P1J9 CDC73
1
CDC73 [nucleoplasm]
(R-HSA-3322360)
0.462
2
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