SIRT1 deacetylates TAF1B in SL1 complex

Stable Identifier
R-HSA-5211239
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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As inferred from mouse, SIRT1, an NAD+ dependent deacetylase, deacetylates the TAF1B (TAF(1)68) subunit of the SL1 complex. Deacetylation of TAF1B inhibits transcription of rRNA genes.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
NAD-dependent protein deacetylase activity of SIRT1 [nucleoplasm]
Physical Entity
Activity
Inferred From
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Reviewed
Created