MAP2K1(2-8) [cytosol]

Stable Identifier
R-HSA-5211342
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
MAP2K1 small LF fragment
MAP2K1(2-8) [cytosol] icon
Locations in the PathwayBrowser for interactor UniProt:Q9H8W4 PKHF2
Literature References
PubMed ID Title Journal Year
9703991 Anthrax lethal factor cleaves the N-terminus of MAPKKs and induces tyrosine/threonine phosphorylation of MAPKs in cultured macrophages

Vitale, G, Pellizzari, R, Recchi, C, Napolitani, G, Mock, M, Montecucco, C

Biochem. Biophys. Res. Commun. 1998
9563949 Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

Duesbery, NS, Webb, CP, Leppla, SH, Gordon, VM, Klimpel, KR, Copeland, TD, Ahn, NG, Oskarsson, MK, Fukasawa, K, Paull, KD, Vande Woude, GF

Science 1998
External Reference Information
External Reference
Gene Names
MAP2K1, MEK1, PRKMK1
Chain
chain:1-393
Other Identifiers
0001740347
1130_at
11717291_a_at
11749555_a_at
11757478_s_at
16802190
1844_s_at
202670_at
3092255
3092256
3092263
3092264
3598663
3598664
3598670
3598671
3598672
3598673
3598688
3598690
3598691
3598692
3598696
3598697
3598700
3598701
3598702
5604
7984319
A_23_P20248
GE57608
GO:0000003
GO:0000165
GO:0000166
GO:0000187
GO:0000278
GO:0000902
GO:0002376
GO:0003674
GO:0004672
GO:0004674
GO:0004708
GO:0004712
GO:0004713
GO:0005078
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005634
GO:0005737
GO:0005739
GO:0005768
GO:0005769
GO:0005770
GO:0005783
GO:0005794
GO:0005815
GO:0005829
GO:0005856
GO:0005886
GO:0005925
GO:0006464
GO:0006468
GO:0006810
GO:0006935
GO:0006950
GO:0007049
GO:0007050
GO:0007165
GO:0007346
GO:0007507
GO:0007568
GO:0008022
GO:0008150
GO:0008283
GO:0008285
GO:0009058
GO:0009790
GO:0010628
GO:0010629
GO:0016020
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0018107
GO:0018108
GO:0019899
GO:0021697
GO:0023014
GO:0030154
GO:0030182
GO:0030216
GO:0030234
GO:0030674
GO:0030878
GO:0031098
GO:0031410
GO:0032147
GO:0032872
GO:0034641
GO:0040011
GO:0043167
GO:0043226
GO:0043539
GO:0045597
GO:0045893
GO:0047485
GO:0048538
GO:0048646
GO:0048679
GO:0048856
GO:0048870
GO:0050772
GO:0060020
GO:0060324
GO:0060425
GO:0060440
GO:0060502
GO:0060674
GO:0060711
GO:0070371
GO:0070374
GO:0071902
GO:0090170
GO:0090398
GO:0097110
GO:1903800
GO:2000641
Hs.3446.0.A2_3p_at
ILMN_1694240
L05624_s_at
L11284_at
PH_hs_0022483
TC15000613.hg
Participant Of
Other forms of this molecule
Disease
Name Identifier Synonyms
anthrax disease 7427
Cross References
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
ZINC - Investigational
ZINC - Metabolites
IntEnz
GeneCards
Orphanet
ZINC - Predictions - Purchasable
Interactors (23)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P15056 BRAF  68 0.977 60
 UniProt:P04049 RAF1  54 0.955 37
 UniProt:P10398 ARAF  4 0.758 7
 UniProt:Q8IVT5 KSR1  5 0.725 9
 UniProt:P31946 YWHAB  1 0.643 4
 UniProt:P28482 MAPK1  18 0.609 2
 UniProt:Q8WWU5-7 TCP11      0.556 3
 UniProt:Q8N9N5-2 BANP      0.556 3
 UniProt:Q9H8W4 PKHF2      0.556 3
 UniProt:P46937 YAP1  7 0.556 3
 UniProt:Q8N9N5 BANP  1 0.556 3
 UniProt:Q9Y297 BTRC  2 0.556 3
 UniProt:Q04917 YWHAH  1 0.527 3
 UniProt:P61981 YWHAG  1 0.527 3
 UniProt:P63104 YWHAZ  2 0.527 4
 UniProt:P62258 YWHAE  1 0.527 3
 UniProt:Q86Y07 VRK2      0.524 2
 UniProt:Q61097  5 0.508 2
 UniProt:Q13526 PIN1  2 0.508 5
 UniProt:P27361 MAPK3  6 0.499 2
 UniProt:Q86Y07-1 VRK2      0.499 2
 UniProt:Q96S96 PEBP4      0.462 3
 UniProt:O75832 PSMD10  2 0.462 2
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