Reactome | COPRS [nucleoplasm]

COPRS [nucleoplasm]

Stable Identifier

R-HSA-5212681

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Coordinator of PRMT5 and differentiation stimulator, COPRS_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NQ92 COPRS

Gene Names

COPRS, C17orf79, COPR5

Chain

chain:1-184

Reference Genes

BioGPS Gene:55352 COPRS

COSMIC (genes):COPRS COPRS

CTD Gene:55352 COPRS

dbSNP Gene:55352 COPRS

ENSEMBL:ENSG00000172301 COPRS

HGNC:28848 COPRS

KEGG Gene (Homo sapiens):55352 COPRS

Monarch:55352 COPRS

NCBI Gene:55352 COPRS

UCSC:Q9NQ92 COPRS

Reference Transcript

RefSeq:NM_018405.3 COPRS

Other Identifiers

0002940129

11727453_a_at

16843179

225096_at

3752425

3752426

3752429

3752430

3752433

3752435

3752436

43462_s_at

46304_at

55352

8014073

A_23_P152858

A_24_P130296

GE55314

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005886

GO:0006325

GO:0006464

GO:0007517

GO:0008150

GO:0042393

GO:0043226

GO:0043985

GO:0048856

GO:0051276

HMNXSV003046029

Hs.8179.0.S1_3p_at

ILMN_1752947

PH_hs_0000876

PH_hs_0030963

TC17001345.hg

Participates

as an input of

COPRS binds CCND1:CDK4:PRMT5:pT5-WDR77 (Homo sapiens)

as a component of

CCND1:CDK4:PRMT5:pT5-WDR77:COPRS [nucleoplasm] (Homo sapiens)

Inferred To

Ghost homologue of COPRS [nucleoplasm] (Danio rerio)

Ghost homologue of COPRS [nucleoplasm] (Sus scrofa)

COPRS [nucleoplasm] (Bos taurus)

COPRS [nucleoplasm] (Canis familiaris)

Coprs [nucleoplasm] (Mus musculus)

Coprs [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_060875.2

OpenTargets

ENSG00000172301

GeneCards

Q9NQ92

HPA

ENSG00000172301-COPRS

Ensembl

ENSP00000304327, ENSG00000172301, ENST00000302362

PRO

Q9NQ92

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14744 PRMT5	3	p-Y297,304,307-PRMT5 [nucleoplasm] (R-HSA-5211300) PRMT5 [cytosol] (R-HSA-191876) PRMT5 [nucleoplasm] (R-HSA-5205609)	0.616	6
UniProt:P62805 H4C1	19	SUMO3-HIST1H4 [nucleoplasm] (R-HSA-4570531) HIST1H4A [extracellular region] (R-HSA-977569) SUMO1-HIST1H4 [nucleoplasm] (R-HSA-4570518) 4xAcK-HIST1H4A [nucleoplasm] (R-HSA-427390) AcK5,12-HIST1H4A [nucleoplasm] (R-HSA-212078) AcK17-HIST1H4 [nucleoplasm] (R-HSA-427469) AcK13-HIST1H4 [nucleoplasm] (R-HSA-4568744) AcK6-HIST1H4 [nucleoplasm] (R-HSA-4568748) AcK17-HIST1H4 [nucleoplasm] (R-HSA-4568749) AcK9-HIST1H4 [nucleoplasm] (R-HSA-4568758) Me2aR4-HIST1H4 [nucleoplasm] (R-HSA-5229015) Me2sR4-HIST1H4 [nucleoplasm] (R-HSA-4754243) MeR4-HIST1H4 [nucleoplasm] (R-HSA-4754240) Me3K21-HIST1H4 [nucleoplasm] (R-HSA-5651656) MeK21-HIST1H4 [nucleoplasm] (R-HSA-5423110) AcK-HIST1H4 [nucleoplasm] (R-HSA-3451124) MeK-HIST1H4A [nucleoplasm] (R-HSA-2172676) HIST1H4 [nucleoplasm] (R-HSA-181902) Me2K21-HIST1H4 [nucleoplasm] (R-HSA-5651652)	0.525	3

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