Reactome | ARL2BP [cytosol]

ARL2BP [cytosol]

Stable Identifier

R-HSA-5215982

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

ADP-ribosylation factor-like protein 2-binding protein, AR2BP_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Y2Y0 ARL2BP

Gene Names

ARL2BP, BART, BART1

Chain

chain:1-163

Reference Genes

BioGPS Gene:23568 ARL2BP

COSMIC (genes):ARL2BP ARL2BP

CTD Gene:23568 ARL2BP

dbSNP Gene:23568 ARL2BP

ENSEMBL:ENSG00000102931 ARL2BP

ENSEMBL_homo_sapiens_GENE:ENSG00000102931.8 ARL2BP

HGNC:17146 ARL2BP

KEGG Gene (Homo sapiens):23568 ARL2BP

Monarch:23568 ARL2BP

NCBI Gene:23568 ARL2BP

OMIM:615407 ARL2BP

UCSC:Q9Y2Y0 ARL2BP

Reference Transcript

RefSeq:NM_012106.3 ARL2BP

Other Identifiers

11716707_a_at

11749287_a_at

11757304_s_at

16819469

202092_PM_s_at

202092_s_at

23568

33198_at

3662651

3662652

3662654

3662655

3662656

3662657

3662660

3662661

3662662

3662663

3662664

3775119

3775120

7996012

A_23_P15182

GE62062

GO:0003713

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005758

GO:0005759

GO:0005813

GO:0005815

GO:0005819

GO:0005829

GO:0005856

GO:0005929

GO:0006351

GO:0006355

GO:0007165

GO:0023052

GO:0030496

GO:0030695

GO:0036211

GO:0042531

GO:0042995

GO:0043226

GO:0045893

GO:0051457

GO:0098772

GO:0140110

HMNXSV003028999

Hs.9552.0.S1_3p_a_at

ILMN_1755391

PH_hs_0000983

TC16000485.hg

Participates

as an input of

ARL2:GTP binds ARL2BP (Homo sapiens)

as a component of

ARL2:GTP:ARL2BP [cytosol] (Homo sapiens)

Other forms of this molecule

ARL2BP [mitochondrial matrix]

Inferred To

arl2bp [cytosol] (Danio rerio)

arl2bp [cytosol] (Xenopus tropicalis)

Arl2bp [cytosol] (Mus musculus)

Arl2bp [cytosol] (Rattus norvegicus)

ARL2BP [cytosol] (Bos taurus)

ARL2BP [cytosol] (Canis familiaris)

ARL2BP [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_036238.1

OpenTargets

ENSG00000102931

GeneCards

Q9Y2Y0

HPA

ENSG00000102931-ARL2BP

Ensembl

ENSG00000102931, ENSP00000219204, ENST00000219204

PRO

Q9Y2Y0

Pharos - Targets

Q9Y2Y0

Orphanet

22276

PDB

3DOE, 2K9A, 3DOF

HMDB Protein

HMDBP08300

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P36404 ARL2	2	ARL2 [cytosol] (R-HSA-5216230) ARL2 [mitochondrial matrix] (R-HSA-5250216)	0.966	27
UniProt:P36405 ARL3	1	ARL3 [cilium] (R-HSA-5618182)	0.841	8
UniProt:Q9Y6A4 CFA20			0.793	8
UniProt:Q9Y649 Q9Y649			0.556	3
UniProt:P22607 FGFR3	20	FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853144) FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853131) FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853152) FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853124) FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853125) FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853127) FGFR3 K650T [plasma membrane] (R-HSA-1614411) FGFR3 K650N [plasma membrane] (R-HSA-1614406) FGFR3 K650M [plasma membrane] (R-HSA-1614402) FGFR3 K650Q [plasma membrane] (R-HSA-1614410) FGFR3 A391E [plasma membrane] (R-HSA-1614390) FGFR3 K650E [plasma membrane] (R-HSA-1614400) FGFR3 G380R [plasma membrane] (R-HSA-1614398) FGFR3 G382D [plasma membrane] (R-HSA-2018740) FGFR3 805fs*141 [plasma membrane] (R-HSA-1614387) FGFR3 [plasma membrane] (R-HSA-2038357) FGFR3 S371C [plasma membrane] (R-HSA-1614421) FGFR3 Y373C [plasma membrane] (R-HSA-1614424) FGFR3 G370C [plasma membrane] (R-HSA-1614394) FGFR3 R248C [plasma membrane] (R-HSA-1614419)	0.556	3
UniProt:P46379-2 BAG6			0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:P06396 GSN	7	GSN(200-270) [extracellular region] (R-HSA-976940) GSN [secretory granule lumen] (R-HSA-6801486) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3
UniProt:P17987 TCP1	1	TCP1 [cytosol] (R-HSA-390448)	0.556	3

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