Reactome | SYP [clathrin-sculpted glutamate transport vesicle membrane]

SYP [clathrin-sculpted glutamate transport vesicle membrane]

Stable Identifier

R-HSA-5215991

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

clathrin-sculpted glutamate transport vesicle membrane

Synonyms

Synaptophysin, SYPH_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P08247 SYP

Gene Names

SYP

Chain

chain:1-313

Reference Genes

BioGPS Gene:6855 SYP

COSMIC (genes):SYP SYP

CTD Gene:6855 SYP

dbSNP Gene:6855 SYP

ENSEMBL:ENSG00000102003 SYP

HGNC:11506 SYP

Monarch:6855 SYP

NCBI Gene:6855 SYP

OMIM:313475 SYP

UCSC:P08247 SYP

Reference Transcript

RefSeq:NM_003179.2 SYP

Other Identifiers

11725033_a_at

11725034_at

11747728_a_at

17110835

213200_PM_at

213200_at

2987645

37182_at

4007900

4007902

4007903

4007904

4007905

4007906

4007907

4007908

4007909

4007911

4007912

4007913

4007914

4007915

4007916

4007917

6855

8172573

A_23_P136936

GE87832

GO:0005515

GO:0006897

GO:0008021

GO:0008289

GO:0010807

GO:0015485

GO:0016020

GO:0016188

GO:0016192

GO:0030672

GO:0031410

GO:0031594

GO:0042169

GO:0042734

GO:0042802

GO:0043005

GO:0043195

GO:0043226

GO:0044306

GO:0045202

GO:0048168

GO:0048169

GO:0048172

GO:0048471

GO:0048499

GO:0048786

GO:0050804

GO:0060076

GO:0061024

GO:0098685

GO:0098793

GO:2000474

HMNXSV003034111

Hs.75667.0.S1_3p_at

ILMN_1701483

PH_hs_0004358

TC0X001029.hg

X06389_at

Participates

as a component of

Cross References

ENSEMBL

ENSP00000418169, ENST00000263233, ENST00000479808, ENSP00000263233

OpenTargets

ENSG00000102003

HPA

ENSG00000102003-SYP

PRO

P08247

Pharos - Targets

P08247

GlyGen

P08247

Orphanet

SYP

HMDB Protein

HMDBP08024

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.666	13
UniProt:Q96T60 PNKP	1	PNKP [nucleoplasm] (R-HSA-5649651)	0.556	3
UniProt:P05067 APP	20	APP(672-713) [extracellular region] (R-HSA-879340) APP(672-711) [cytosol] (R-HSA-877188) APP(672-711) [extracellular region] (R-HSA-976740) APP [endoplasmic reticulum lumen] (R-HSA-8956696) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP(18-770) [endosome lumen] (R-HSA-5229077) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-687) [extracellular region] (R-HSA-9010033) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-770) [extracellular region] (R-HSA-49335) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136)	0.556	3
UniProt:O95363 FARS2	1	FARS2(1-?) [mitochondrial matrix] (R-HSA-379565)	0.556	3
UniProt:O60664 PLIN3	7	p-PLIN3 [lysosomal lumen] (R-HSA-9639396) p-PLIN3 [cytosol] (R-HSA-9613664) p-PLIN3 [lipid droplet] (R-HSA-9613539) PLIN3 [lipid droplet] (R-HSA-9613337) p-PLIN3 [late endosome lumen] (R-HSA-9639393) PLIN3 [cytosol] (R-HSA-6814628) PLIN3 [transport vesicle] (R-HSA-6813900)	0.556	3
UniProt:P53365 ARFIP2	1	ARFIP2 [cytosol] (R-HSA-6813848)	0.556	3
UniProt:Q6IN84 MRM1	1	MRM1 [mitochondrial matrix] (R-HSA-6793088)	0.556	3
UniProt:Q96E11 MRRF	1	MRRF [mitochondrial matrix] (R-HSA-5419265)	0.556	3
UniProt:Q9NR28 DIABLO	2	DIABLO [mitochondrial intermembrane space] (R-HSA-64637) DIABLO [cytosol] (R-HSA-114298)	0.556	3
UniProt:O95971 CD160	1	CD160 [plasma membrane] (R-HSA-198014)	0.556	3
UniProt:O00213 APBB1	1	APBB1 [nucleoplasm] (R-HSA-5683987)	0.527	2
UniProt:Q05823 RNASEL	2	RNASEL [mitochondrial matrix] (R-HSA-5223312) RNASEL [cytosol] (R-HSA-1015684)	0.527	2
UniProt:Q9HD23 MRS2	1	MRS2 [mitochondrial inner membrane] (R-HSA-5216072)	0.527	3
UniProt:Q9H2C2 ARV1	1	ARV1 [endoplasmic reticulum membrane] (R-HSA-5216144)	0.527	2
UniProt:P16260 SLC25A16	1	SLC25A16 [mitochondrial inner membrane] (R-HSA-199229)	0.527	2

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