p-T497-PRKCA [cytosol]

Stable Identifier
R-HSA-5218731
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
PKCA
p-T497-PRKCA [cytosol] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
9889098 Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)

Dutil, EM, Toker, A, Newton, AC

Curr. Biol. 1998
8749392 Protein kinase C is regulated in vivo by three functionally distinct phosphorylations

Keranen, LM, Dutil, EM, Newton, AC

Curr. Biol. 1995
External Reference Information
External Reference
Gene Names
PRKCA, PKCA, PRKACA
Chain
initiator methionine:1, chain:2-672
Reference Transcript
Other Identifiers
0002360341
0006510040
11717471_at
11717472_at
11754557_s_at
1437_at
1560074_at
16837128
206923_at
213093_at
215195_at
32304_at
3731827
3731828
3731829
3731830
3731835
3731869
3731902
3731903
3731925
3731926
3731927
3731928
3731958
3731960
3731962
3731963
3731965
3731981
3731986
3731987
3731998
3731999
3732000
3732001
3732002
3732003
3732004
3732005
3732006
3732007
3732008
38042_at
5578
8009301
A_14_P126156
A_23_P55099
A_24_P916496
GE79113
GE86264
GE86266
GO:0000166
GO:0000278
GO:0000902
GO:0001525
GO:0001938
GO:0002159
GO:0002376
GO:0003674
GO:0004672
GO:0004674
GO:0004697
GO:0004698
GO:0005178
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005783
GO:0005829
GO:0005886
GO:0006464
GO:0006468
GO:0006810
GO:0006915
GO:0006950
GO:0007049
GO:0007077
GO:0007155
GO:0007165
GO:0007267
GO:0007411
GO:0008150
GO:0008219
GO:0008270
GO:0008283
GO:0009056
GO:0010595
GO:0010613
GO:0015031
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0018105
GO:0018107
GO:0019899
GO:0022607
GO:0030154
GO:0030168
GO:0030335
GO:0031666
GO:0031966
GO:0032991
GO:0034330
GO:0034351
GO:0034641
GO:0034655
GO:0035403
GO:0035408
GO:0035556
GO:0035866
GO:0038128
GO:0040011
GO:0042592
GO:0043167
GO:0043226
GO:0043488
GO:0043536
GO:0045651
GO:0045766
GO:0045780
GO:0045785
GO:0045931
GO:0046872
GO:0048471
GO:0048646
GO:0048856
GO:0048870
GO:0050796
GO:0051276
GO:0061024
GO:0070062
GO:0070374
GO:0070555
GO:0090330
GO:0097190
GO:0106071
GO:2000707
Hs.279856.0.S1_3p_at
Hs.80206.1.A1_3p_at
Hs2.389532.1.S1_3p_at
ILMN_1771800
PH_hs_0023925
TC17000783.hg
X52479_at
g4506066_3p_at
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name
O-phospho-L-threonine at 497
Coordinate
497
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
ZINC - Investigational
IntEnz
GeneCards
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (5)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P00533 EGFR  59 0.635 3
 UniProt:Q02156 PRKCE  2 0.564 2
 UniProt:P11309-2 PIM1      0.544 2
 UniProt:P05129 PRKCG  1 0.527 3
 UniProt:P34901 Sdc4  26 0.482 2
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