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MYBBP1A [nucleoplasm]
Stable Identifier
R-HSA-5250650
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Myb-binding protein 1A, MBB1A_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Positive epigenetic regulation of rRNA expression (Homo sapiens)
B-WICH complex positively regulates rRNA expression (Homo sapiens)
B-WICH complex binds rDNA promoter (Homo sapiens)
B-WICH:rDNA Promoter:SL1:RNA Pol I [nucleoplasm] (Homo sapiens)
B-WICH [nucleoplasm] (Homo sapiens)
MYBBP1A [nucleoplasm] (Homo sapiens)
MYBBP1A [nucleoplasm] (Homo sapiens)
B-WICH recruits histone acetyltransferases (Homo sapiens)
B-WICH:rDNA Promoter:KAT2B:KAT2A:EP300 [nucleoplasm] (Homo sapiens)
B-WICH:rDNA Promoter:SL1:RNA Pol I [nucleoplasm] (Homo sapiens)
B-WICH [nucleoplasm] (Homo sapiens)
MYBBP1A [nucleoplasm] (Homo sapiens)
B-WICH:rDNA Promoter:SL1:RNA Pol I [nucleoplasm] (Homo sapiens)
B-WICH [nucleoplasm] (Homo sapiens)
MYBBP1A [nucleoplasm] (Homo sapiens)
B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 (Homo sapiens)
B-WICH:rDNA Promoter:KAT2B:KAT2A:EP300 [nucleoplasm] (Homo sapiens)
B-WICH:rDNA Promoter:SL1:RNA Pol I [nucleoplasm] (Homo sapiens)
B-WICH [nucleoplasm] (Homo sapiens)
MYBBP1A [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BQG0 MYBBP1A
Gene Names
MYBBP1A, P160
Chain
chain:1-1328
Reference Genes
BioGPS Gene:10514 MYBBP1A
COSMIC (genes):MYBBP1A MYBBP1A
CTD Gene:10514 MYBBP1A
dbSNP Gene:10514 MYBBP1A
ENSEMBL:ENSG00000132382 MYBBP1A
HGNC:7546 MYBBP1A
Monarch:10514 MYBBP1A
NCBI Gene:10514 MYBBP1A
OMIM:604885 MYBBP1A
UCSC:Q9BQG0 MYBBP1A
Reference Transcript
RefSeq:NM_014520.3 MYBBP1A
RefSeq:NM_001105538.1 MYBBP1A
Other Identifiers
10514
11722495_a_at
11735880_a_at
11735881_x_at
11745429_x_at
11750032_a_at
16840018
219098_PM_at
219098_at
233803_PM_s_at
233803_s_at
3742131
3742132
3742133
3742134
3742135
3742136
3742137
3742138
3742139
3742140
3742141
3742142
3742143
3742144
3742145
3742146
3742147
3742148
3742149
3742150
3742151
3742152
3742153
3742154
3742156
3742157
3742158
3742159
3742160
3742161
3742162
3742163
3742164
3742165
3742167
3742168
3742169
3742170
3742171
3742172
3742173
3742174
3742175
3742176
3742177
3742178
3742179
49628_at
8011640
A_23_P78170
GE58597
GO:0001649
GO:0003677
GO:0003714
GO:0003723
GO:0005634
GO:0005654
GO:0005730
GO:0005737
GO:0006091
GO:0006325
GO:0006338
GO:0006355
GO:0008134
GO:0016020
GO:0022904
GO:0030154
GO:0032922
GO:0042149
GO:0042254
GO:0042564
GO:0043226
GO:0043231
GO:0043565
GO:0045892
GO:0045943
GO:0045944
GO:0045945
GO:0048511
GO:0060090
GO:0070888
GO:0072332
GO:0110016
GO:0140110
GO:1903450
GO:2000210
HMNXSV003025153
HMNXSV003040132
HMNXSV003054716
Hs.22824.2.S1_3p_a_at
ILMN_1806757
PH_hs_0001997
TC17001023.hg
TC17002451.hg
g7657350_3p_at
Participates
as an input of
B-WICH complex binds rDNA promoter (Homo sapiens)
as a component of
B-WICH [nucleoplasm] (Homo sapiens)
Inferred To
Mybbp1a [nucleoplasm]
(Mus musculus)
Mybbp1a [nucleoplasm]
(Rattus norvegicus)
MYBBP1A [nucleoplasm]
(Bos taurus)
MYBBP1A [nucleoplasm]
(Caenorhabditis elegans)
MYBBP1A [nucleoplasm]
(Canis familiaris)
MYBBP1A [nucleoplasm]
(Gallus gallus)
MYBBP1A [nucleoplasm]
(Sus scrofa)
Cross References
ENSEMBL
ENST00000381556
,
ENST00000254718
,
ENSP00000370968
,
ENSP00000254718
OpenTargets
ENSG00000132382
HPA
ENSG00000132382-MYBBP1A
PRO
Q9BQG0
Pharos - Targets
Q9BQG0
GlyGen
Q9BQG0
HMDB Protein
HMDBP09383
Interactors (11)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P06748 NPM1
11
NPM1 [cytosol]
(R-HSA-3008211)
p-S4-NPM1 [cytosol]
(R-HSA-6801679)
NPM1 [nucleoplasm]
(R-HSA-606320)
NPM1 [granular component]
(R-HSA-9017702)
NPM1(1-117)-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699834)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [cytosol]
(R-HSA-9699861)
NPM1(1-117)-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730697)
NPM1(1-117)-p-7Y-ALK(1068-1620) fusion [cytosol]
(R-HSA-9730703)
NPM1(1-117)-p-7Y-ALK(1058-1620) fusion [nucleoplasm]
(R-HSA-9725010)
polySUMO2,3-K263-NPM1 [nucleoplasm]
(R-HSA-4086056)
monoSUMO1-K263-NPM1 [nucleoplasm]
(R-HSA-4086039)
0.712
4
UniProt:P62753 RPS6
4
RPS6 [cytosol]
(R-HSA-72381)
p-5S-RPS6 [cytosol]
(R-HSA-165727)
3OHR147-RPS6 [cytosol]
(R-HSA-9629876)
RPS6 [nucleoplasm]
(R-HSA-6790606)
0.569
3
UniProt:Q9NX58 LYAR
0.564
2
UniProt:Q9NY93 DDX56
0.564
2
UniProt:P01106 MYC
2
MYC [nucleoplasm]
(R-HSA-188379)
PolyUb-MYC [nucleoplasm]
(R-HSA-6783169)
0.564
2
UniProt:P49711 CTCF
1
CTCF [nucleoplasm]
(R-HSA-3782562)
0.527
2
UniProt:Q9NR30 DDX21
1
DDX21 [nucleoplasm]
(R-HSA-5250652)
0.483
3
UniProt:P13569 CFTR
17
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR [endosome membrane]
(R-HSA-6782965)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [lysosomal membrane]
(R-HSA-5627279)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
0.483
11
UniProt:Q8WYQ5 DGCR8
1
DGCR8 [nucleoplasm]
(R-HSA-1482509)
0.483
2
UniProt:Q92731 ESR2
5
ESR2 [cytosol]
(R-HSA-9020970)
ESR2 [nucleoplasm]
(R-HSA-446165)
Me-PalmS-ESR2 [plasma membrane]
(R-HSA-9637787)
PalmS-ESR2 [plasma membrane]
(R-HSA-9021059)
PalmS-ESR2 [cytosol]
(R-HSA-9020979)
0.462
2
UniProt:P03372 ESR1
10
ESR1 [cytosol]
(R-HSA-9020968)
ESR1 [nucleoplasm]
(R-HSA-446168)
Me260-PalmS-ESR1 [plasma membrane]
(R-HSA-9637788)
PalmS-ESR1 [plasma membrane]
(R-HSA-9021057)
PalmS-ESR1 [cytosol]
(R-HSA-9020974)
Me260-ESR1 [cytosol]
(R-HSA-9632177)
p-S167-ESR1 [cytosol]
(R-HSA-9841254)
p-S167-ESR1 [nucleoplasm]
(R-HSA-9841867)
monoSUMO1-5K-ESR1 [nucleoplasm]
(R-HSA-4090302)
p-S118-ESR1 [nucleoplasm]
(R-HSA-9024210)
0.462
2
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