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BAG1 [cytosol]
Stable Identifier
R-HSA-5255443
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
BAG family molecular chaperone regulator 1, BAG1_HUMAN
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to heat stress (Homo sapiens)
Regulation of HSF1-mediated heat shock response (Homo sapiens)
HSP110s exchange ATP for ADP on HSP70s:ADP (Homo sapiens)
HSP70 NEFs [cytosol] (Homo sapiens)
BAG1-5 [cytosol] (Homo sapiens)
BAG1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q99933 BAG1
Gene Names
BAG1, HAP
Chain
chain:1-345
Reference Genes
BioGPS Gene:573 BAG1
COSMIC (genes):BAG1 BAG1
CTD Gene:573 BAG1
dbSNP Gene:573 BAG1
ENSEMBL:ENSG00000107262 BAG1
ENSEMBL_homo_sapiens_GENE:ENSG00000107262.26 BAG1
HGNC:937 BAG1
KEGG Gene (Homo sapiens):573 BAG1
Monarch:573 BAG1
NCBI Gene:573 BAG1
OMIM:601497 BAG1
UCSC:Q99933 BAG1
Reference Transcript
RefSeq:NM_004323.5 BAG1
RefSeq:NM_001172415.1 BAG1
Other Identifiers
11716127_a_at
11753334_x_at
11754751_x_at
11755255_a_at
17093204
202387_PM_at
202387_at
211475_PM_s_at
211475_s_at
229720_PM_at
229720_at
3203486
3203487
3203488
3203489
3203490
3203491
3203493
3203495
3203497
3203499
3203501
3203504
3203505
3203506
3203507
3203508
3203509
3203510
34798_at
47643_at
573
71009_at
80600_s_at
8160647
A_23_P146654
A_33_P3290919
A_33_P3290924
GE58332
GO:0000774
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006457
GO:0006915
GO:0007166
GO:0012501
GO:0016020
GO:0023052
GO:0031625
GO:0043066
GO:0043226
GO:0043231
GO:0050821
GO:0051085
GO:0051087
GO:0098772
HMNXSV003043154
Hs.99395.0.A1_3p_at
ILMN_1733970
PH_hs_0021929
PH_hs_0024287
TC09001009.hg
TC09002454.hg
Z35491_at
g4583370_3p_a_at
g7549801_3p_at
Participates
as a member of
BAG1-5 [cytosol] (Homo sapiens)
Inferred To
si:dkey-216e9.4 [cytosol]
(Danio rerio)
bag102 [cytosol]
(Schizosaccharomyces pombe)
bag-1 [cytosol]
(Caenorhabditis elegans)
BAG1 [cytosol]
(Bos taurus)
BAG1 [cytosol]
(Canis familiaris)
BAG1 [cytosol]
(Sus scrofa)
Bag1 [cytosol]
(Mus musculus)
Bag1 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_004314.5
,
NP_001165886.1
OpenTargets
ENSG00000107262
GeneCards
Q99933
HPA
ENSG00000107262-BAG1
Ensembl
ENST00000634734
,
ENSP00000369026
,
ENSP00000489189
,
ENST00000379704
,
ENSG00000107262
PRO
Q99933
Pharos - Targets
Q99933
PDB
5AQL
,
3FZF
,
5AQV
,
5AQK
,
5AQO
,
5AQN
,
3LDQ
,
5AQT
,
3M3Z
,
5AQU
,
5AQM
,
3FZH
,
5AQQ
,
5AQP
,
1WXV
,
5AQR
,
5AQG
,
5AQS
,
3FZK
,
5AQF
,
3FZL
,
5AQJ
,
1HX1
,
5AQI
,
3FZM
,
5AQH
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P14373 TRIM27
2
TRIM27 [nucleoplasm]
(R-HSA-2997690)
TRIM27 [cytosol]
(R-HSA-8851002)
0.781
7
UniProt:P11142 HSPA8
10
Me3K561-HSPA8 [nucleoplasm]
(R-HSA-8932217)
HSPA8 [secretory granule lumen]
(R-HSA-6801530)
HSPA8 [extracellular region]
(R-HSA-6805936)
HSPA8 [ficolin-1-rich granule lumen]
(R-HSA-6801494)
HSPA8 [nucleoplasm]
(R-HSA-5082380)
HSPA8 [plasma membrane]
(R-HSA-936508)
HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane]
(R-HSA-888599)
HSPA8 [late endosome lumen]
(R-HSA-9631104)
HSPA8 [lysosomal lumen]
(R-HSA-9625182)
HSPA8 [cytosol]
(R-HSA-264476)
0.719
13
UniProt:P04049 RAF1
20
p-S621-RAF1 S259F [cytosol]
(R-HSA-9656124)
p-S621-RAF1 S257L [cytosol]
(R-HSA-9656121)
p-S621-RAF1 P261L [cytosol]
(R-HSA-9656106)
p-S621-RAF1 N262K [cytosol]
(R-HSA-9656101)
p-S621-RAF1 P261A [cytosol]
(R-HSA-9656103)
p-S621-RAF1 P261S [cytosol]
(R-HSA-9656113)
p-S621-RAF1 S259T [cytosol]
(R-HSA-9656130)
p-S621-RAF1 P261T [cytosol]
(R-HSA-9656115)
p-S621-RAF1 P261R [cytosol]
(R-HSA-9656110)
p-S621-RAF1 S259P [cytosol]
(R-HSA-9656127)
p-S621-RAF1 T260I [cytosol]
(R-HSA-9656136)
p-S621-RAF1 T260R [cytosol]
(R-HSA-9656139)
p-S621-RAF1 V263A [cytosol]
(R-HSA-9656148)
p-S621-RAF1 R256S [cytosol]
(R-HSA-9656119)
p-S621-RAF1 T491I [cytosol]
(R-HSA-9656143)
p-S621-RAF1 D486N [cytosol]
(R-HSA-9656088)
p-S621-RAF1 S427G [cytosol]
(R-HSA-9656134)
p-S621-RAF1 L613V [cytosol]
(R-HSA-9656098)
p-S621-RAF1 G361A [cytosol]
(R-HSA-9656092)
p-S621-RAF1 G370R [cytosol]
(R-HSA-9656094)
0.508
2
UniProt:Q9UNE7 STUB1
1
STUB1 [cytosol]
(R-HSA-975970)
0.499
2
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