TCF7L2 K485fs25* [nucleoplasm]

Stable Identifier
R-HSA-5334040
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
16547505 TCF-4 isoforms absent in TCF-4 mutated MSI-H colorectal cancer cells colocalize with nuclear CtBP and repress TCF-4-mediated transcription

Cuilliere-Dartigues, P, El-Bchiri, J, Krimi, A, Buhard, O, Fontanges, P, Fléjou, JF, Hamelin, R, Duval, A

Oncogene 2006
10919662 The human T-cell transcription factor-4 gene: structure, extensive characterization of alternative splicings, and mutational analysis in colorectal cancer cell lines

Duval, A, Rolland, S, Tubacher, E, Bui, H, Thomas, G, Hamelin, R

Cancer Res. 2000
External Reference Information
External Reference
Gene Names
TCF7L2, TCF4
Chain
chain:1-619
Other Identifiers
11746313_a_at
11746314_s_at
11746315_x_at
11746404_a_at
11747829_x_at
11751102_x_at
11755181_a_at
16709333
212759_s_at
212761_at
212762_s_at
216035_x_at
216037_x_at
216511_s_at
32025_at
3264622
3264623
3264624
3264626
3264627
3264633
3264652
3264659
3264685
3264689
3264692
3264696
3264697
3264698
3264699
3264708
3264710
3264712
3264714
3264722
3264723
3264724
3264725
3264726
48528_at
6934
7930537
A_14_P125103
A_14_P133398
A_23_P127013
A_23_P389588
A_24_P921823
A_33_P3377304
GE83165
GO:0000122
GO:0000228
GO:0000790
GO:0000976
GO:0000978
GO:0000981
GO:0001103
GO:0001228
GO:0001568
GO:0003674
GO:0003677
GO:0003682
GO:0003700
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0006259
GO:0006357
GO:0006810
GO:0006913
GO:0007049
GO:0007050
GO:0007165
GO:0007223
GO:0007267
GO:0008013
GO:0008134
GO:0008150
GO:0008219
GO:0008283
GO:0009058
GO:0009749
GO:0010909
GO:0015031
GO:0016055
GO:0016605
GO:0019899
GO:0019901
GO:0022607
GO:0030154
GO:0031016
GO:0032024
GO:0032092
GO:0032350
GO:0032991
GO:0032993
GO:0034641
GO:0035257
GO:0042592
GO:0042593
GO:0043226
GO:0043433
GO:0043565
GO:0043570
GO:0044334
GO:0045295
GO:0045444
GO:0045892
GO:0045944
GO:0046827
GO:0048625
GO:0048660
GO:0048856
GO:0050679
GO:0051276
GO:0051897
GO:0060070
GO:0065003
GO:0070016
GO:0070369
GO:0090090
GO:1904837
GO:2000675
GO:2001237
Hs.173638.0.S1_3p_s_at
Hs.173638.0.S2_3p_s_at
Hs.173638.0.S3_3p_a_at
Hs.173638.0.S3_3p_at
Hs.173638.1.S1_3p_x_at
Hs.173638.2.S1_3p_a_at
Hs.173638.2.S1_3p_x_at
Hs.283857.0.S1_3p_s_at
ILMN_1672486
TC10000820.hg
TC10002300.hg
Y11306_rna1_at
Participant Of
Other forms of this molecule
Modified Residues
Name
Replacement of residues 485 to 506 by SAFATYKVKAAASAHPLQMEAY
Disease
Name Identifier Synonyms
stomach cancer 10534 malignant neoplasm of greater curvature of stomach, unspecified, malignant neoplasm of lesser curvature of stomach, NOS, malignant tumor of body of stomach (disorder), neoplasm of stomach (disorder), Ca lesser curvature - stomach (disorder), malignant neoplasm of greater curve of stomach unspecified (disorder), Ca body - stomach, ca lesser curvature of stomach, ca greater curvature of stomach, malignant neoplasm of lesser curvature of stomach, unspecified, malignant tumor of lesser curve of stomach (disorder), malignant neoplasm of body of stomach, gastric neoplasm, malignant neoplasm of greater curvature of stomach, NOS, Ca body - stomach (disorder), stomach neoplasm, Ca greater curvature - stomach (disorder), malignant neoplasm of lesser curve of stomach unspecified (disorder), malignant tumor of greater curve of stomach (disorder)
colorectal cancer 9256
Interactors (6)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P35222 CTNNB1  33 0.97 27
 UniProt:Q13761 RUNX3  7 0.656 14
 UniProt:Q08050 FOXM1  3 0.612 7
 UniProt:Q14526 HIC1  2 0.61 6
 UniProt:P09874 PARP1  4 0.597 6
 UniProt:Q9UER7 DAXX  2 0.543 5
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