FABPs bind LCFAs

Stable Identifier
R-HSA-5334794
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Hydrophobic compounds such as long-chain fatty acids (LCFAs) and their acyl-CoA derivatives (LCFA-CoAs) are involved in important functions within a cell such as membrane substrates, energy sources and signalling molecules. The hydrophobic nature of these compounds makes translocation between different compartments of a cell extremely difficult. Fatty acid-binding proteins (FABPs) are able to bind these hydrophobic compounds with high affinity and transport them through the cytosol for delivery to different organelles within the cell. To date, 9 human FABP-coding genes have been identified (Smathers & Petersen 2011).

Literature References
PubMed ID Title Journal Year
21504868 The human fatty acid-binding protein family: evolutionary divergences and functions

Smathers, RL, Petersen, DR

Hum. Genomics 2011
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Orthologous Events
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