TCF7L2 R397W [nucleoplasm]

Stable Identifier
R-HSA-5339696
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
TCF7L2 R397W [nucleoplasm] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
18621708 A genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancer

Dodge, M, Lum, L, Gundapaneni, D, Michnoff, C, Tang, W, Roth, M

Proc. Natl. Acad. Sci. U.S.A. 2008
Participates
Other forms of this molecule
Modified Residues
Name
L-arginine 397 replaced with L-tryptophan
Coordinate
397
PsiMod
A protein modification that effectively converts a source amino acid residue to L-tryptophan.
A protein modification that effectively removes or replaces an L-arginine.
Disease
Name Identifier Synonyms
colorectal cancer DOID:9256
Interactors (6)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P35222 CTNNB1  20 0.97 27
 UniProt:Q13761 RUNX3  7 0.656 14
 UniProt:Q08050 FOXM1  3 0.612 7
 UniProt:Q14526 HIC1  2 0.61 6
 UniProt:P09874 PARP1  4 0.597 6
 UniProt:Q9UER7 DAXX  13 0.543 5
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