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WFS1 [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-535474
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
Wolframin, WFS1_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Unfolded Protein Response (UPR) (Homo sapiens)
IRE1alpha activates chaperones (Homo sapiens)
XBP1(S) activates chaperone genes (Homo sapiens)
Expression of WFS1 (Homo sapiens)
WFS1 [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O76024 WFS1
Gene Names
WFS1
Chain
chain:1-890
Reference Genes
BioGPS Gene:7466 WFS1
COSMIC (genes):WFS1 WFS1
CTD Gene:7466 WFS1
dbSNP Gene:7466 WFS1
ENSEMBL:ENSG00000109501 WFS1
HGNC:12762 WFS1
KEGG Gene (Homo sapiens):7466 WFS1
Monarch:7466 WFS1
NCBI Gene:7466 WFS1
OMIM:606201 WFS1
UCSC:O76024 WFS1
Reference Transcript
RefSeq:NM_006005.3 WFS1
RefSeq:NM_001145853.1 WFS1
Other Identifiers
0000780605
11751105_s_at
1555270_a_at
16964676
202908_at
2716955
2716961
2716962
2716966
2716968
2716969
2716970
2716974
2716976
2716977
2716978
2716979
29128
35164_at
7466
8093906
A0A0S2Z4V6
A_23_P121499
AAC64943
AAH30130
AC116317
AF084481
AK312897
ALQ33853
BAG35744
BC030130
CAA77022
CCDS3386
CH471131
EAW82396
EAW82397
EAW82398
ENSG00000109501
ENSP00000226760
ENSP00000423337
ENST00000226760
ENST00000226760.5
ENST00000503569
ENST00000503569.5
EntrezGene:7466
EntrezGene:WFS1
g13376995_3p_at
GE62440
GO:0000122
GO:0001822
GO:0003091
GO:0003674
GO:0005515
GO:0005516
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005783
GO:0005788
GO:0005789
GO:0006457
GO:0006464
GO:0006810
GO:0006950
GO:0006983
GO:0007165
GO:0007601
GO:0007605
GO:0008134
GO:0008150
GO:0008219
GO:0009056
GO:0009058
GO:0016020
GO:0016021
GO:0019899
GO:0022417
GO:0030176
GO:0030285
GO:0030425
GO:0030433
GO:0030968
GO:0031016
GO:0031398
GO:0031410
GO:0031625
GO:0032469
GO:0033613
GO:0034641
GO:0034976
GO:0036498
GO:0040007
GO:0042048
GO:0042592
GO:0042593
GO:0043069
GO:0043226
GO:0043433
GO:0043524
GO:0043687
GO:0044267
GO:0045927
GO:0048306
GO:0048856
GO:0050821
GO:0050877
GO:0051117
GO:0051247
GO:0051604
GO:0051928
GO:0055074
GO:0070628
GO:1902236
GO:1903892
GO:2000675
HGNC:12762
HPA029128
Hs2.26077.2.S1_3p_s_at
ILMN_1759023
IPR011990
IPR026208
IPR026209
KU178395
MIM:116400
MIM:125853
MIM:222300
MIM:600965
MIM:606201
MIM:614296
NM_001145853
NM_006005
NP_001139325
NP_005996
PH_hs_0002300
PR02060
PR02061
TC04000068.hg
UPI00000715C3
WFS1
WFS1-201
WFS1-202
XM_017008586
XP_016864075
Y18064
Participant Of
output
Expression of WFS1
Other forms of this molecule
p-WFS1 [endoplasmic reticulum lumen]
WFS1 [endoplasmic reticulum lumen]
Cross References
RefSeq
NP_005996.2
,
NP_001139325.1
OpenTargets
ENSG00000109501
GeneCards
O76024
PRO
O76024
Orphanet
15721
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P54274 TERF1
1
TERF1 [nucleoplasm]
(R-HSA-164618)
0.508
2
UniProt:Q5JX71 F209A
0.488
2
UniProt:P11912 CD79A
2
CD79A [plasma membrane]
(R-HSA-197154)
p-Y188,Y199-CD79A [plasma membrane]
(R-HSA-983539)
0.488
2
UniProt:Q13520 AQP6
1
AQP6 [transport vesicle membrane]
(R-HSA-431741)
0.488
2
UniProt:A5PKU2 A5PKU2
0.488
2
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