Reactome | PDIA5 [endoplasmic reticulum membrane]

PDIA5 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-535514

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Protein disulfide-isomerase A5, PDIA5_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q14508 WFDC2

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External Reference Information

External Reference

UniProt:Q14554 PDIA5

Gene Names

PDIA5, PDIR

Chain

signal peptide:1-21, chain:22-519

Reference Genes

BioGPS Gene:10954 PDIA5

COSMIC (genes):PDIA5 PDIA5

CTD Gene:10954 PDIA5

dbSNP Gene:10954 PDIA5

ENSEMBL:ENSG00000065485 PDIA5

HGNC:24811 PDIA5

Monarch:10954 PDIA5

NCBI Gene:10954 PDIA5

UCSC:Q14554 PDIA5

Reference Transcript

RefSeq:NM_006810.3 PDIA5

Other Identifiers

10954

11716919_a_at

16944738

203857_PM_s_at

203857_s_at

2639230

2639231

2639232

2639233

2639234

2639235

2639240

2639241

2639242

2639250

2639252

2639256

2639257

2639258

2639262

2639264

2639266

2639272

2639273

2639274

2639276

2639277

2639280

2639281

2639283

2639284

2639285

2639286

2639287

2639318

2639325

2639326

2639328

2639329

2639330

37044_at

8082133

A_14_P110360

A_14_P117180

A_23_P167040

A_33_P3254634

D49490_at

GE57229

GE79743

GO:0003756

GO:0003824

GO:0005515

GO:0005737

GO:0005783

GO:0005788

GO:0005789

GO:0006091

GO:0006457

GO:0012505

GO:0015035

GO:0016491

GO:0016853

GO:0022900

GO:0043226

GO:0043231

GO:0140096

HMNXSV003016931

HMNXSV003035282

ILMN_1695763

PH_hs_0004437

TC03002498.hg

TC03003363.hg

g5803120_3p_a_at

Participates

as an output of

Expression of PDIA5 (Homo sapiens)

Cross References

ENSEMBL

ENST00000489923, ENSP00000323313, ENSP00000417520, ENST00000316218

OpenTargets

ENSG00000065485

HPA

ENSG00000065485-PDIA5

PRO

Q14554

Pharos - Targets

Q14554

GlyGen

Q14554

PDB

4I6X

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
IntAct:EBI-10171679 386682			0.556	3
UniProt:Q99750 MDFI			0.556	3
UniProt:P60409 KRTAP10-7	1	KRTAP10-7 [cytosol] (R-HSA-6810279)	0.556	3
UniProt:Q13061 TRDN	1	TRDN [sarcoplasmic reticulum lumen] (R-HSA-2855215)	0.527	3
UniProt:Q99538 LGMN	2	LGMN [endolysosome lumen] (R-HSA-8942384) LGMN [lysosomal lumen] (R-HSA-350135)	0.527	2
UniProt:O00584 RNASET2	2	RNASET2 [extracellular region] (R-HSA-6806248) RNASET2 [azurophil granule lumen] (R-HSA-6799345)	0.527	3
UniProt:Q9H6X2 ANTXR1			0.527	3
UniProt:P04066 FUCA1	3	FUCA1 [lysosomal lumen] (R-HSA-5693804) FUCA1 [extracellular region] (R-HSA-6806209) FUCA1 [azurophil granule lumen] (R-HSA-6798773)	0.527	2
UniProt:Q9Y2B0 CNPY2			0.527	3
UniProt:O00626 CCL22	1	CCL22(25-93) [extracellular region] (R-HSA-443980)	0.527	2
UniProt:Q96DR8 MUCL1	18	GalNAc-MUCL1 [plasma membrane] (R-HSA-8858459) Core 2 (MUCL1) [Golgi lumen] (R-HSA-1462316) Core 2a (MUCL1) [Golgi lumen] (R-HSA-6784294) GalNAc-MUCL1 [Golgi lumen] (R-HSA-913643) Sialyl Tn antigen (MUCL1) [Golgi lumen] (R-HSA-1463594) T-antigen (MUCL1) [Golgi lumen] (R-HSA-1462357) Sialyl-2,3 T-antigen (MUCL1) [Golgi lumen] (R-HSA-1463467) Sialyl T-antigen (MUCL1) [Golgi lumen] (R-HSA-1463524) Disialyl T-antigen (MUCL1) [Golgi lumen] (R-HSA-1463480) MUCL1 [Golgi lumen] (R-HSA-913632) Core 6 (MUCL1) [Golgi lumen] (R-HSA-1462246) extended Core 6 (MUCL1) [Golgi lumen] (R-HSA-1967042) Core 7 (MUCL1) [Golgi lumen] (R-HSA-1462181) Core 3 (MUCL1) [Golgi lumen] (R-HSA-1462268) Core 4 (MUCL1) [Golgi lumen] (R-HSA-1462139) Core 5 (MUCL1) [Golgi lumen] (R-HSA-1462337) Core 2S (MUCL1) [Golgi lumen] (R-HSA-6786344) Core 8 (MUCL1) [Golgi lumen] (R-HSA-1462256)	0.527	2
UniProt:Q14508 WFDC2	1	WFDC2 [extracellular region] (R-HSA-9830363)	0.527	2
UniProt:Q9UMX5 NENF			0.527	2
UniProt:Q969H8 C19orf10	1	C19orf10 [endoplasmic reticulum lumen] (R-HSA-535584)	0.499	2

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