PAK1-3 autophosphorylates

Stable Identifier
R-HSA-5357472
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Increased PAK1-3 catalytic activity is associated with autophosphorylation of key residues, including one site in the regulatory portion (S144 in PAK1) and another in the so-called activation loop (T423 in PAK1).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of PAK1,2,3 dimer [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed