Reactome | MRPL53 [mitochondrial inner membrane]

MRPL53 [mitochondrial inner membrane]

Stable Identifier

R-HSA-5368226

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

39S ribosomal protein L53, mitochondrial, RM53_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q96EL3 MRPL53

Gene Names

MRPL53

Chain

transit peptide:1-, chain:-112

Reference Genes

BioGPS Gene:116540 MRPL53

COSMIC (genes):MRPL53 MRPL53

CTD Gene:116540 MRPL53

dbSNP Gene:116540 MRPL53

ENSEMBL:ENSG00000204822 MRPL53

ENSEMBL_homo_sapiens_GENE:ENSG00000204822.7 MRPL53

HGNC:16684 MRPL53

KEGG Gene (Homo sapiens):116540 MRPL53

Monarch:116540 MRPL53

NCBI Gene:116540 MRPL53

OMIM:611857 MRPL53

UCSC:Q96EL3 MRPL53

Reference Transcript

RefSeq:NM_053050.4 MRPL53

Other Identifiers

116540

11717260_at

16899263

225523_PM_at

225523_at

2560142

2560143

2560144

2560145

52178_at

8053165

A_23_P102258

A_24_P371194

GE526095

GO:0005515

GO:0005739

GO:0005743

GO:0005762

GO:0005840

GO:0032543

GO:0043226

GO:0140053

GO:1990904

HMNXSV003043674

Hs.48563.0.A1_3p_at

ILMN_1813682

PH_hs_0019916

TC02005034.hg

Participates

as a component of

39S ribosomal subunit [mitochondrial inner membrane] (Homo sapiens)

Inferred To

CH1073-423L13.1 [mitochondrial inner membrane] (Danio rerio)

MRPL53 [mitochondrial inner membrane] (Bos taurus)

MRPL53 [mitochondrial inner membrane] (Gallus gallus)

mRpL53 [mitochondrial inner membrane] (Drosophila melanogaster)

mrpl-53 [mitochondrial inner membrane] (Caenorhabditis elegans)

Ghost homologue of MRPL53 [mitochondrial inner membrane] (Canis familiaris)

Ghost homologue of MRPL53 [mitochondrial inner membrane] (Rattus norvegicus)

Ghost homologue of MRPL53 [mitochondrial inner membrane] (Sus scrofa)

Mrpl53 [mitochondrial inner membrane] (Mus musculus)

Cross References

RefSeq

NP_444278.1

OpenTargets

ENSG00000204822

GeneCards

Q96EL3

HPA

ENSG00000204822-MRPL53

Ensembl

ENSG00000204822, ENSP00000258105, ENST00000258105

PRO

Q96EL3

Pharos - Targets

Q96EL3

PDB

8OIT, 7OF6, 6ZSA, 6NU3, 6ZSD, 7A5F, 7L08, 7A5H, 7OID, 7OG4, 7OF2, 6ZSG, 6VLZ, 6ZM5, 7OIC, 7OI6, 7OF3, 7PO4, 7A5J, 6ZS9, 7OF4, 5OOM, 6ZM6, 6VMI, 7QI4, 6NU2, 7OF5, 3J9M, 7QI5, 7PD3, 3J7Y, 7O9K, 7OF7, 6ZSC, 7O9M, 7L20, 7OI9, 6ZSB, 8OIR, 7OIB, 7A5G, 7OIA, 7A5I, 8ANY, 7OF0, 6ZSE, 7OIE, 7A5K, 6I9R, 7ODR, 5OOL, 7ODS, 7OI8, 7QI6, 7ODT, 7OI7

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q15370 ELOB	2	TCEB2 [nucleoplasm] (R-HSA-112423) ELOB [cytosol] (R-HSA-180551)	0.556	5
UniProt:P26367 PAX6	1	PAX6 [nucleoplasm] (R-HSA-3009044)	0.556	3

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