Reactome | MRPS18B [mitochondrial inner membrane]

MRPS18B [mitochondrial inner membrane]

Stable Identifier

R-HSA-5368234

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial inner membrane

Synonyms

28S ribosomal protein S18b, mitochondrial, RT18B_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9Y676 MRPS18B

Gene Names

MRPS18B, C6orf14, HSPC183, PTD017

Chain

transit peptide:1-35, chain:36-258

Reference Genes

BioGPS Gene:28973 MRPS18B

COSMIC (genes):MRPS18B MRPS18B

CTD Gene:28973 MRPS18B

dbSNP Gene:28973 MRPS18B

ENSEMBL:ENSG00000203624.10 MRPS18B

ENSEMBL:ENSG00000204568 MRPS18B

ENSEMBL:ENSG00000204568.12 MRPS18B

ENSEMBL:ENSG00000223775.8 MRPS18B

ENSEMBL:ENSG00000226111.8 MRPS18B

ENSEMBL:ENSG00000227420.8 MRPS18B

ENSEMBL:ENSG00000229861.8 MRPS18B

ENSEMBL:ENSG00000233813.8 MRPS18B

HGNC:14516 MRPS18B

KEGG Gene (Homo sapiens):28973 MRPS18B

Monarch:28973 MRPS18B

NCBI Gene:28973 MRPS18B

OMIM:611982 MRPS18B

UCSC:Q9Y676 MRPS18B

Reference Transcript

RefSeq:NM_014046.3 MRPS18B

Other Identifiers

0006590180

11746187_x_at

11754356_x_at

17006324

17027506

17030351

17033056

17035176

17037835

17040549

208907_PM_s_at

208907_s_at

217408_PM_at

217408_at

28973

2901824

2901825

2901826

2901828

2901830

2901832

2901834

2901836

2901837

2901838

2901839

2901840

2901842

2901843

2901844

32221_at

8117955

8177824

8179139

A_14_P101539

A_23_P59107

A_33_P3336992

GE61838

GO:0003674

GO:0003735

GO:0005198

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005743

GO:0005763

GO:0005840

GO:0006412

GO:0008150

GO:0030054

GO:0032543

GO:0032991

GO:0043226

GO:0140053

HMNXSV003036402

Hs.274417.2.S1_3p_at

ILMN_1721337

ILMN_2121282

PH_hs_0014163

PH_hs_0032419

TC06000343.hg

TC6_cox_hap2000041.hg

TC6_dbb_hap3000034.hg

TC6_mann_hap4000036.hg

TC6_mcf_hap5000028.hg

TC6_qbl_hap6000034.hg

TC6_ssto_hap7000034.hg

g13529220_3p_a_at

Participates

as a member of

MRPS18A,B,C [mitochondrial inner membrane] (Homo sapiens)

Inferred To

mrps-18b [mitochondrial inner membrane] (Caenorhabditis elegans)

mRpS18B [mitochondrial inner membrane] (Drosophila melanogaster)

MRPS18B [mitochondrial inner membrane] (Bos taurus)

MRPS18B [mitochondrial inner membrane] (Canis familiaris)

MRPS18B [mitochondrial inner membrane] (Sus scrofa)

MRPS18B [mitochondrial inner membrane] (Xenopus tropicalis)

wu:fj45h02 [mitochondrial inner membrane] (Danio rerio)

Mrps18b [mitochondrial inner membrane] (Mus musculus)

Mrps18b [mitochondrial inner membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_054765.1

OpenTargets

ENSG00000204568

HPA

ENSG00000204568-MRPS18B

GeneCards

Q9Y676

Ensembl

ENSG00000204568, ENSP00000415703, ENSG00000203624, ENST00000259873, ENST00000426945, ENSP00000397790, ENSP00000398494, ENST00000412451, ENSP00000383438, ENST00000451032, ENSG00000223775, ENST00000430402, ENSP00000414972, ENST00000327800, ENSP00000402718, ENST00000454427, ENSG00000227420, ENSG00000229861, ENSG00000233813, ENSP00000259873, ENSG00000226111

PRO

Q9Y676

Pharos - Targets

Q9Y676

PDB

6RW4, 6ZSG, 6ZSE, 6VLZ, 7A5I, 7A5K, 6ZSA, 6ZSB, 6RW5, 6ZM5, 7A5F, 7L08, 6NU2, 6ZSC, 6ZM6, 6ZS9, 6VMI, 6NU3, 7A5G, 7OG4, 6ZSD, 3J9M

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75396 SEC22B	6	SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.556	3
UniProt:P24593 IGFBP5	5	IGFBP5 [extracellular region] (R-HSA-381414) IGFBP5(21-163) [extracellular region] (R-HSA-381415) IGFBP5(164-272) [extracellular region] (R-HSA-381478) IGFBP5 [endoplasmic reticulum lumen] (R-HSA-8956738) p-IGFBP5 [endoplasmic reticulum lumen] (R-HSA-8956988)	0.556	3
UniProt:Q8N2H4 SYS1	1	SYS1 [trans-Golgi network membrane] (R-HSA-6813921)	0.556	3
UniProt:P78382 SLC35A1	2	SLC35A1 [Golgi membrane] (R-HSA-727812) SLC35A1 V93Cfs*17 [Golgi membrane] (R-HSA-5651957)	0.556	3
UniProt:O43561-2 LAT	2	p-5Y-LAT-2 [plasma membrane] (R-HSA-2396597) LAT-2 [plasma membrane] (R-HSA-2396548)	0.556	3
UniProt:P06400 RB1	20	RB1 R661W [nucleoplasm] (R-HSA-9659801) RB1 C706F [nucleoplasm] (R-HSA-9659812) RB1 N480del [nucleoplasm] (R-HSA-9659792) RB1 C706Y [nucleoplasm] (R-HSA-9659821) RB1 R661Q [nucleoplasm] (R-HSA-9659807) RB1 I703_E737del [nucleoplasm] (R-HSA-9661065) RB1 R830_G887del [cytosol] (R-HSA-9661059) RB1 K791* [cytosol] (R-HSA-9662284) RB1 Q176* [cytosol] (R-HSA-9661774) RB1 S114* [cytosol] (R-HSA-9661775) RB1 K765* [cytosol] (R-HSA-9662281) RB1 W99* [cytosol] (R-HSA-9661769) RB1 S149* [cytosol] (R-HSA-9661770) RB1 E166* [cytosol] (R-HSA-9661767) RB1 G100* [cytosol] (R-HSA-9661763) RB1 E125* [cytosol] (R-HSA-9661784) RB1 Q121* [cytosol] (R-HSA-9661780) RB1 E184* [cytosol] (R-HSA-9661781) RB1 E137* [cytosol] (R-HSA-9661782) RB1 K745* [cytosol] (R-HSA-9662288)	0.525	2

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