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TWISTNB
Stable Identifier
R-HSA-5419290
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
DNA-directed RNA polymerase I subunit RPA43, RPA43_HUMAN
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Negative epigenetic regulation of rRNA expression (Homo sapiens)
NoRC negatively regulates rRNA expression (Homo sapiens)
Transcription of intergenic spacer of the rRNA gene (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
Positive epigenetic regulation of rRNA expression (Homo sapiens)
B-WICH complex positively regulates rRNA expression (Homo sapiens)
B-WICH complex binds rDNA promoter (Homo sapiens)
B-WICH:rDNA Promoter:SL1:RNA Pol I [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
B-WICH recruits histone acetyltransferases (Homo sapiens)
B-WICH:rDNA Promoter:KAT2B:KAT2A:EP300 [nucleoplasm] (Homo sapiens)
B-WICH:rDNA Promoter:SL1:RNA Pol I [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
B-WICH:rDNA Promoter:SL1:RNA Pol I [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 (Homo sapiens)
B-WICH:rDNA Promoter:KAT2B:KAT2A:EP300 [nucleoplasm] (Homo sapiens)
B-WICH:rDNA Promoter:SL1:RNA Pol I [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription (Homo sapiens)
RNA Polymerase I Chain Elongation (Homo sapiens)
Elongation of pre-rRNA transcript (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
RNA Polymerase I Promoter Clearance (Homo sapiens)
RNA Polymerase I Promoter Escape (Homo sapiens)
Loss of Rrn3 from RNA Polymerase I promoter escape complex (Homo sapiens)
RNA Polymerase I Transcription Initiation complex [nucleoplasm] (Homo sapiens)
Active RNA Polymerase I [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription Initiation (Homo sapiens)
Assembly of RNA Polymerase I Holoenzyme (human) (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
Binding of RRN3 to RNA Polymerase I (Homo sapiens)
Active RNA Polymerase I [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Homo sapiens)
Active RNA Polymerase I [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription Initiation complex [nucleoplasm] (Homo sapiens)
Active RNA Polymerase I [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription Termination (Homo sapiens)
Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box (Homo sapiens)
PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box (Homo sapiens)
PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
Polymerase I Transcription Complex/Nascent Pre rRNA Complex pauses at the TTF-I:Sal Box (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I Holoenzyme [nucleoplasm] (Homo sapiens)
TWISTNB [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q3B726 TWISTNB
Gene Names
TWISTNB
Chain
chain:1-338
Reference Genes
BioGPS Gene:221830 TWISTNB
COSMIC (genes):TWISTNB TWISTNB
CTD Gene:221830 TWISTNB
dbSNP Gene:221830 TWISTNB
ENSEMBL:ENSG00000105849 TWISTNB
ENSEMBL:ENSG00000105849 TWISTNB
HGNC:18027 TWISTNB
KEGG Gene (Homo sapiens):hsa:221830 TWISTNB
Monarch:221830 TWISTNB
NCBI Gene:221830 TWISTNB
OMIM:608312 TWISTNB
UCSC:Q3B726 TWISTNB
Reference Transcript
RefSeq:NM_001002926.1 TWISTNB
Other Identifiers
0006370292
11725395_at
11725396_at
11725397_at
17055630
19071
214729_at
221830
22416
226784_at
3040455
3040456
3040457
3040458
3040459
3040460
3040462
3040463
3040464
35007_at
46114_at
56651_at
8138454
A_23_P386561
A_23_P82474
AAH14574
AAI30299
AAI30301
AK301329
BAH13460
BC014574
BC130298
BC130300
BK000492
CCDS34606
CH236948
CH471073
DAA05732
EAL24277
EAW93714
ENSG00000105849
ENSP00000222567
ENST00000222567
EntrezGene:221830
GE53996
GO:0001054
GO:0003674
GO:0003899
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005730
GO:0005736
GO:0006351
GO:0006361
GO:0006362
GO:0006363
GO:0008150
GO:0009058
GO:0016779
GO:0034641
GO:0043226
GO:0045815
GO:1990830
HGNC:18027
HPA019071
HPA022416
Hs.55896.0.S1_3p_at
Hs.55896.1.S1_3p_a_at
Hs.55896.1.S1_3p_x_at
ILMN_1781121
IPR005576
MIM:608312
NM_001002926
NP_001002926
PF03876
PH_hs_0032817
TC07001177.hg
TWISTNB
TWISTNB-201
uc003sup.2
UPI000006CEF4
Participant Of
input
Assembly of RNA Polymerase I Holoenzyme (human)
hasComponent
RNA Polymerase I Holoenzyme [nucleoplasm]
Inferred To
Ghost homologue of TWISTNB [nucleoplasm] (Saccharomyces cerevisiae)
Homologues of TWISTNB [nucleoplasm] (Canis familiaris)
TWISTNB [nucleoplasm] (Bos taurus)
TWISTNB [nucleoplasm] (Canis familiaris)
TWISTNB [nucleoplasm] (Danio rerio)
TWISTNB [nucleoplasm] (Dictyostelium discoideum)
TWISTNB [nucleoplasm] (Drosophila melanogaster)
TWISTNB [nucleoplasm] (Gallus gallus)
TWISTNB [nucleoplasm] (Mus musculus)
TWISTNB [nucleoplasm] (Rattus norvegicus)
TWISTNB [nucleoplasm] (Sus scrofa)
TWISTNB [nucleoplasm] (Taeniopygia guttata)
TWISTNB [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
NP_001002926.1
GeneCards
Q3B726
PRO
Q3B726
HMDB Protein
HMDBP11910
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