Reactome | CDC5L [nucleoplasm]

CDC5L [nucleoplasm]

Stable Identifier

R-HSA-5420887

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Cell division cycle 5-like protein, CDC5L_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q99459 CDC5L

Gene Names

CDC5L, KIAA0432, PCDC5RP

Chain

chain:1-802

Reference Genes

BioGPS Gene:988 CDC5L

COSMIC (genes):CDC5L CDC5L

CTD Gene:988 CDC5L

dbSNP Gene:988 CDC5L

ENSEMBL:ENSG00000096401 CDC5L

HGNC:1743 CDC5L

KEGG Gene (Homo sapiens):988 CDC5L

Monarch:988 CDC5L

NCBI Gene:988 CDC5L

OMIM:602868 CDC5L

UCSC:Q99459 CDC5L

Reference Transcript

RefSeq:NM_001253.3 CDC5L

Other Identifiers

0002060722

11719080_a_at

11719081_a_at

1621_at

17009262

209055_s_at

209056_s_at

209057_x_at

2908573

2908574

2908575

2908576

2908577

2908579

2908580

2908581

2908582

2908584

2908585

2908587

2908588

2908589

2908590

2908591

2908592

2908594

2908600

2908601

2908602

2908603

2908604

32040_i_at

32041_r_at

8120022

988

A_14_P100735

A_14_P125269

A_23_P156471

A_32_P55804

D85423_at

GE53182

GO:0000228

GO:0000278

GO:0000398

GO:0000974

GO:0000977

GO:0000981

GO:0001222

GO:0001228

GO:0003674

GO:0003677

GO:0003700

GO:0003723

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005662

GO:0005681

GO:0005694

GO:0005737

GO:0006259

GO:0006281

GO:0006397

GO:0006950

GO:0006974

GO:0007049

GO:0007165

GO:0008134

GO:0008150

GO:0008157

GO:0008380

GO:0009058

GO:0016020

GO:0016607

GO:0019899

GO:0019901

GO:0032991

GO:0032993

GO:0034641

GO:0043226

GO:0043522

GO:0044344

GO:0045944

GO:0048471

GO:0071007

GO:0071013

GO:0071352

GO:0071987

GO:0072422

GO:1904568

GO:1990090

GO:1990646

Hs.155174.0.S1_3p_a_at

Hs.155174.0.S2_3p_a_at

ILMN_1652907

PH_hs_0025923

TC06000617.hg

g2887434_3p_a_at

Participant Of

hasComponent

PRP19-CDC5L complex [nucleoplasm]

Inferred To

cdc-5l [nucleoplasm] (Caenorhabditis elegans)

Cdc5 [nucleoplasm] (Drosophila melanogaster)

Cdc5l [nucleoplasm] (Mus musculus)

Cdc5l [nucleoplasm] (Rattus norvegicus)

CDC5L [nucleoplasm] (Canis familiaris)

CDC5L [nucleoplasm] (Gallus gallus)

CDC5L [nucleoplasm] (Sus scrofa)

cdc5l [nucleoplasm] (Danio rerio)

cdc5l [nucleoplasm] (Dictyostelium discoideum)

cdc5l [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_001244.1

OpenTargets

ENSG00000096401

HPA

ENSG00000096401-CDC5L

GeneCards

Q99459

Ensembl

ENSP00000360532, ENST00000371477, ENSG00000096401

PRO

Q99459

Orphanet

26169

PDB

2DIN, 5Z58, 5MQF, 6FF4, 6ID1, 2DIM, 5XJC, 6ID0, 6ICZ, 5Z57, 6QDV, 5YZG, 5Z56, 6FF7

Interactors (18)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08379 GOLGA2	3	GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.718	6
UniProt:O60341 KDM1A	1	KDM1A [nucleoplasm] (R-HSA-996769)	0.667	3
UniProt:P52272 HNRNPM	1	HNRNPM [nucleoplasm] (R-HSA-71949)	0.644	7
UniProt:P62136 PPP1CA	1	PPP1CA [cytosol] (R-HSA-163525)	0.59	2
UniProt:P07910 HNRNPC	2	HNRNPC [nucleoplasm] (R-HSA-71933) SUMO1-K250-HNRNPC [nucleoplasm] (R-HSA-4570543)	0.564	2
UniProt:Q9CSN1 Snw1	1	Snw1 [nucleoplasm] (R-MMU-2065315)	0.564	2
UniProt:P40222 TXLNA	1	TXLNA [cytosol] (R-HSA-449124)	0.556	3
UniProt:Q9UGI0 ZRANB1	1	ZRANB1 [cytosol] (R-HSA-6781939)	0.556	3
UniProt:P63104 YWHAZ	2	YWHAZ [cytosol] (R-HSA-206099) YWHAZ [nucleoplasm] (R-HSA-450469)	0.553	2
UniProt:Q9BZJ0 CRNKL1	1	CRNKL1 [nucleoplasm] (R-HSA-8867899)	0.553	2
UniProt:Q9UPT5 EXOC7	2	EXOC7 [cytosol] (R-HSA-5623386) EXOC7 [plasma membrane] (R-HSA-2872288)	0.547	2
UniProt:Q9Y5B9 SUPT16H	1	SUPT16H [nucleoplasm] (R-HSA-112415)	0.547	2
UniProt:Q13535 ATR	1	ATR [nucleoplasm] (R-HSA-912443)	0.544	3
UniProt:Q13616 CUL1	3	CUL1 [nucleoplasm] (R-HSA-187551) G76-NEDD8-K720-CUL1 [cytosol] (R-HSA-8952519) CUL1 [cytosol] (R-HSA-174230)	0.527	2
UniProt:P38919 EIF4A3	2	EIF4A3 [nucleoplasm] (R-HSA-8849149) EIF4A3 [cytosol] (R-HSA-927868)	0.527	2
UniProt:Q9UJV9 DDX41	3	K48polyUb-DDX41 [cytosol] (R-HSA-3134942) DDX41 [cytosol] (R-HSA-3134807) K48polyUb-DDX41 [cytosol] (R-HSA-3134941)	0.527	2
UniProt:P62304 SNRPE	2	SNRPE [nucleoplasm] (R-HSA-71905) SNRPE [cytosol] (R-HSA-191782)	0.527	2
UniProt:Q13573 SNW1	1	SNW1 [nucleoplasm] (R-HSA-351663)	0.527	3