AFBDHD hydrolyses non-enzymatically to AFBDHO

Stable Identifier
R-HSA-5423694
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Aflatoxin B1-8,9-dihydrodiol (AFBDHD) undergoes base-catalysed rearrangement to aflatoxin B1 dialdehyde (AFBDHO) that can react with protein lysine residues (not shown here) (Guengerich et al. 1998).

Literature References
PubMed ID Title Journal Year
9675258 Activation and detoxication of aflatoxin B1

Guengerich, FP, Johnson, WW, Shimada, T, Ueng, YF, Yamazaki, H, Langou√ęt, S

Mutat. Res. 1998
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