Unknown NAT transfers COCH3 to AFXBO-C, AFNBO-C

Stable Identifier
R-HSA-5433066
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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An unknown cysteine-S-conjugate N-acetyltransferase (NAT) catalyses the transfer of an acetyl group from acetyl CoA (Ac-CoA) to the exo and endo forms of aflatoxin B1-cysteinyl conjugates (AFXBO-C, AFNBO-C). The resultant N-acetylcysteine-S-conjugate is termed a mercapturic acid which is readily excreted in urine (Hinchman & Ballatori 1994).

Literature References
PubMed ID Title Journal Year
8145281 Glutathione conjugation and conversion to mercapturic acids can occur as an intrahepatic process

Hinchman, CA, Ballatori, N

J Toxicol Environ Health 1994
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
cysteine-S-conjugate N-acetyltransferase activity of unknown NAT [cytosol]
Physical Entity
Activity
Authored
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Created