FADD [cytosol]

Stable Identifier
R-HSA-54639
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
FADD protein (FAS-associating death domain-containing protein) (Mediator of receptor induced toxicity), FADD protein, FAS-associating death domain-containing protein, Mediator of receptor induced toxicity
FADD [cytosol] icon
Locations in the PathwayBrowser for interactor UniProt:Q13158 FADD
Literature References
PubMed ID Title Journal Year
7538907 FADD, a novel death domain-containing protein, interacts with the death domain of Fas and initiates apoptosis

Chinnaiyan, AM, O'Rourke, K, Tewari, M, Dixit, VM

Cell 1995
External Reference Information
External Reference
Gene Names
FADD, MORT1, GIG3
Chain
chain:1-208
Reference Transcript
Other Identifiers
0006350164
11716799_at
11716800_at
16728331
202535_at
3338425
3338426
3338427
3338428
3338431
3338432
3338433
3338434
3338435
38755_at
7942168
A_14_P110132
A_14_P123448
A_23_P86917
A_24_P278637
GE60092
GO:0001822
GO:0001916
GO:0002020
GO:0002376
GO:0002821
GO:0003674
GO:0005123
GO:0005164
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006915
GO:0006919
GO:0006950
GO:0007155
GO:0007165
GO:0007166
GO:0008150
GO:0008219
GO:0008283
GO:0008625
GO:0009058
GO:0016032
GO:0019899
GO:0022607
GO:0030154
GO:0031264
GO:0031265
GO:0032729
GO:0032757
GO:0032760
GO:0032813
GO:0032991
GO:0033077
GO:0033612
GO:0034138
GO:0034641
GO:0035666
GO:0035877
GO:0036462
GO:0040011
GO:0042104
GO:0042220
GO:0042592
GO:0042802
GO:0042981
GO:0043005
GO:0043029
GO:0043065
GO:0043123
GO:0043226
GO:0043278
GO:0044297
GO:0044403
GO:0044877
GO:0045087
GO:0045121
GO:0045651
GO:0045862
GO:0045944
GO:0048148
GO:0048535
GO:0048536
GO:0048538
GO:0048856
GO:0048870
GO:0051604
GO:0051607
GO:0060340
GO:0060544
GO:0060546
GO:0065003
GO:0070236
GO:0071260
GO:0071550
GO:0089720
GO:0097049
GO:0097190
GO:0097191
GO:0097192
GO:0097202
GO:0097342
GO:0097527
GO:1902041
GO:1902042
GO:2000454
GO:2001238
ILMN_1758658
PH_hs_0004852
TC11000723.hg
X84709_at
g4505228_3p_at
Participant Of
Inferred To
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
Interactors (31)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q14790 CASP8  8 0.978 45
 UniProt:P25445 FAS  1 0.959 22
 UniProt:P50591 TNFSF10  1 0.913 19
 UniProt:Q13158 FADD  1 0.885 12
 UniProt:P25445-1 FAS      0.883 17
 UniProt:Q13546 RIPK1  9 0.866 10
 UniProt:Q15628 TRADD  1 0.806 7
 UniProt:P25446  1 0.772 8
 UniProt:P48023 FASLG  1 0.758 4
 UniProt:Q92851 CASP10  4 0.75 4
 UniProt:P53350 PLK1  4 0.676 9
 UniProt:Q99497 PARK7  7 0.653 9
 UniProt:O00220 TNFRSF10A  1 0.643 4
 UniProt:P03126 VE6      0.593 4
 UniProt:B7UI21 B7UI21      0.593 7
 UniProt:O95243 MBD4  1 0.581 6
 UniProt:Q99836 MYD88  9 0.573 3
 UniProt:Q14790-5 CASP8      0.567 4
 UniProt:Q15560 TCEA2      0.556 3
 UniProt:P62324 BTG1  1 0.556 5
 UniProt:Q9UJ78-2 Q9UJ782      0.556 3
 UniProt:Q7KZS0 Q7KZS0      0.556 3
 UniProt:Q96D03 DDT4L      0.556 3
 UniProt:Q6PEW1 ZCH12      0.556 3
 UniProt:P78317 RNF4  2 0.556 5
 UniProt:B7ZLH0 B7ZLH0      0.556 3
 UniProt:O00560 SDCBP  3 0.556 6
 UniProt:Q9Y6K9 IKBKG  12 0.527 2
 IntAct:EBI-16074260 EHECNLEB1      0.508 2
 UniProt:Q5S007 LRRK2  1 0.499 4
 UniProt:Q14790-1 CASP8      0.482 5