Reactome | UGGT1 [endoplasmic reticulum lumen]

UGGT1 [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-548864

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

UDP-glucose:glycoprotein glucosyltransferase 1, UGGG1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NYU2 UGGT1

Gene Names

UGGT1, GT, UGCGL1, UGGT, UGT1, UGTR

Chain

signal peptide:1-42, chain:43-1555

Reference Genes

BioGPS Gene:56886 UGGT1

COSMIC (genes):UGGT1 UGGT1

CTD Gene:56886 UGGT1

dbSNP Gene:56886 UGGT1

ENSEMBL:ENSG00000136731 UGGT1

ENSEMBL_homo_sapiens_GENE:ENSG00000136731.13 UGGT1

HGNC:15663 UGGT1

KEGG Gene (Homo sapiens):56886 UGGT1

Monarch:56886 UGGT1

NCBI Gene:56886 UGGT1

OMIM:605897 UGGT1

UCSC:Q9NYU2 UGGT1

Reference Transcript

RefSeq:NM_020120.3 UGGT1

Other Identifiers

11729794_at

11729795_s_at

11742021_a_at

16885432

218257_PM_s_at

218257_s_at

222568_PM_at

222568_at

222569_PM_at

222569_at

231968_PM_at

231968_at

244814_PM_at

244814_at

2504884

2504885

2504886

2504889

2504890

2504892

2504894

2504895

2504896

2504899

2504901

2504902

2504903

2504904

2504906

2504907

2504908

2504909

2504912

2504917

2504919

2504920

2504924

2504926

2504929

2504930

2504932

2504933

2504935

2504936

2504938

2504939

2504941

2504942

2504945

2504946

2504947

2504949

2504951

2504952

2504953

2504954

2504956

2504958

2504962

2504963

2504964

2504965

2504966

2504967

2504968

2504969

2504985

2504986

2504988

2504989

4004826

4004830

41970_at

52538_at

56886

60215_at

75131_at

8045090

81335_at

87956_at

89751_at

A_23_P255011

A_33_P3366246

GE80104

GE87572

GO:0003824

GO:0003980

GO:0005515

GO:0005576

GO:0005615

GO:0005783

GO:0005788

GO:0005793

GO:0006457

GO:0006486

GO:0016740

GO:0016757

GO:0018279

GO:0030163

GO:0032991

GO:0036211

GO:0043226

GO:0051082

GO:0051084

GO:0055086

GO:0070062

GO:0071704

GO:0071712

GO:0097359

GO:1901135

HMNXSV003044127

Hs.105794.0.S2_3p_at

Hs.105794.0.S3_3p_at

Hs.124660.1.S1_3p_at

Hs.87070.0.A1_3p_at

ILMN_1755462

ILMN_2360291

PH_hs_0005886

TC02000791.hg

TC02003566.hg

g9910279_3p_a_at

Participates

as a member of

UGGT1,2 [endoplasmic reticulum lumen] (Homo sapiens)

Cross References

RefSeq

NP_064505.1

OpenTargets

ENSG00000136731

HPA

ENSG00000136731-UGGT1

GeneCards

Q9NYU2

Ensembl

ENST00000259253, ENSG00000136731, ENSP00000259253

PRO

Q9NYU2

Pharos - Targets

Q9NYU2

HMDB Protein

HMDBP08093

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	10
UniProt:P04578 env	7	Surface protein gp120 (P04578) [cytosol] (R-HIV-189269) Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) ENV [viral envelope] (R-HIV-173439) Surface protein gp120 [viral envelope] (R-HIV-171211)	0.462	2