AFXBO-SG, AFNBO-SG translocate from cytosol to extracellular region

Stable Identifier
R-HSA-5490230
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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As glutathione conjugates of aflatoxin exo-and endo-epoxides are secreted from the cell, they undergo several hydrolysis steps before they form the mercapturic acid form which is excreted in urine (Heisterkamp et al. 2008). The mechanism of translocation is unknown.

Literature References
PubMed ID Title Journal Year
18357469 The human gamma-glutamyltransferase gene family

Heisterkamp, N, Groffen, J, Warburton, D, Sneddon, TP

Hum Genet 2008
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