Expression of CRYPTOCHROME-1

Stable Identifier
R-HSA-549467
Type
Reaction [omitted]
Species
Homo sapiens
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The CRYPTOCHROME-1 (CRY1) gene is transcribed to yield mRNA and the mRNA is translated to yield protein. CRY1 mRNA and protein show circadian expression. The promoter of the CRY1 gene contains an E-box which is bound by the BMAL1:CLOCK (ARNTL:CLOCK) heterodimer (and probably also the BMAL1:NPAS2 heterodimer), which activates transcription of CRY1.

Literature References
PubMed ID Title Journal Year
14507900 Expression of the blue-light receptor cryptochrome in the human retina

Thompson, CL, Bowes Rickman, C, Shaw, SJ, Ebright, JN, Kelly, U, Sancar, A, Rickman, DW

Invest Ophthalmol Vis Sci 2003
8921389 Cloning, tissue expression, and mapping of a human photolyase homolog with similarity to plant blue-light receptors

van der Spek, PJ, Kobayashi, K, Bootsma, D, Takao, M, Eker, AP, Yasui, A

Genomics 1996
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