Reactome | MED9 [nucleoplasm]

MED9 [nucleoplasm]

Stable Identifier

R-HSA-556804

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Mediator of RNA polymerase II transcription subunit 9, MED9_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism (Homo sapiens)

- Metabolism of lipids (Homo sapiens)
  - Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) (Homo sapiens)
    - PPARA activates gene expression (Homo sapiens)
      - Expression of ANGPTL4 (Homo sapiens)
        
        PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] (Homo sapiens)
        
        Mediator Complex (consensus) [nucleoplasm] (Homo sapiens)
        
        MED9 [nucleoplasm] (Homo sapiens)
      - Expression of CD36 (platelet glycoprotein IV, FAT) (Homo sapiens)
        
        PPARG:Fatty Acid:RXRA:Mediator:Coactivator Complex [nucleoplasm] (Homo sapiens)
        
        Mediator Complex (consensus) [nucleoplasm] (Homo sapiens)
        
        MED9 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9NWA0 MED9

Gene Names

MED9, MED25

Chain

initiator methionine:1, chain:2-146

Reference Genes

BioGPS Gene:55090 MED9

COSMIC (genes):MED9 MED9

CTD Gene:55090 MED9

dbSNP Gene:55090 MED9

ENSEMBL:ENSG00000141026 MED9

ENSEMBL_homo_sapiens_GENE:ENSG00000141026 MED9

HGNC:25487 MED9

KEGG Gene (Homo sapiens):55090 MED9

Monarch:55090 MED9

NCBI Gene:55090 MED9

OMIM:609878 MED9

UCSC:Q9NWA0 MED9

Reference Transcript

RefSeq:NM_018019.2 MED9

Other Identifiers

0003120487

11718668_at

11718669_x_at

11718670_at

16831614

218372_at

3712597

3712598

3712599

3712606

3712607

3712608

45145_at

49187_at

55090

56415

63149_at

8005260

A_23_P66402

AAI04989

AAI12030

AK001055

BAA91483

BC104988

BC112029

CCDS11184

CH471196

EAW55706

ENSG00000141026

ENSP00000268711

ENST00000268711

EntrezGene:55090

g8922272_3p_at

GE87617

GO:0000988

GO:0003674

GO:0003712

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005654

GO:0006357

GO:0008150

GO:0009058

GO:0016592

GO:0032991

GO:0034641

GO:0043226

HGNC:25487

HPA056415

ILMN_1794108

ILMN_1807371

IPR011425

IPR037212

IPR039242

MED9

MED9-201

MIM:609878

NM_018019

NP_060489

PF07544

PH_hs_0012814

TC17000199.hg

uc002grh.2

UPI000006F39B

Participant Of

hasComponent

Mediator Complex (consensus) [nucleoplasm]

Cross References

RefSeq

NP_060489.1

OpenTargets

ENSG00000141026

GeneCards

Q9NWA0

PRO

Q9NWA0

Orphanet

25790

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49336 CDK8	1	CDK8 [nucleoplasm] (R-HSA-212440)	0.812	8
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.757	10
UniProt:Q9BTT4 MED10	1	MED10 [nucleoplasm] (R-HSA-212410)	0.71	5
UniProt:Q93074 MED12	1	MED12 [nucleoplasm] (R-HSA-212343)	0.643	3
UniProt:Q15648 MED1	1	MED1 [nucleoplasm] (R-HSA-212445)	0.643	5
UniProt:O95402 MED26	1	MED26 [nucleoplasm] (R-HSA-556783)	0.643	5
UniProt:O75448 MED24	1	MED24 [nucleoplasm] (R-HSA-212331)	0.527	2
UniProt:Q9Y3C7 MED31	1	MED31 [nucleoplasm] (R-HSA-212429)	0.527	2
UniProt:O75586 MED6	1	MED6 [nucleoplasm] (R-HSA-212359)	0.527	2
UniProt:Q9UHV7 MED13	1	MED13 [nucleoplasm] (R-HSA-212391)	0.527	2
UniProt:Q96G25 MED8	1	MED8 [nucleoplasm] (R-HSA-556784)	0.527	3
UniProt:Q9NVC6 MED17	1	MED17 [nucleoplasm] (R-HSA-212401)	0.527	3
UniProt:Q9Y2X0 MED16	1	MED16 [nucleoplasm] (R-HSA-556802)	0.527	2
UniProt:O60244 MED14	1	MED14 [nucleoplasm] (R-HSA-212441)	0.527	2
UniProt:Q96HR3 MED30	1	MED30 [nucleoplasm] (R-HSA-212398)	0.527	2
UniProt:Q71SY5 MED25	1	MED25 [nucleoplasm] (R-HSA-212414)	0.527	2
UniProt:Q6P2C8 MED27	1	MED27 [nucleoplasm] (R-HSA-556761)	0.527	2
UniProt:O43513 MED7	1	MED7 [nucleoplasm] (R-HSA-212430)	0.527	2
UniProt:Q9H944 MED20	1	MED20 [nucleoplasm] (R-HSA-212428)	0.527	2