Reactome | MED29 [nucleoplasm]

MED29 [nucleoplasm]

Stable Identifier

R-HSA-556821

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Mediator of RNA polymerase II transcription subunit 29, MED29_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - Respiratory Syncytial Virus Infection Pathway (Homo sapiens)
      - RSV-host interactions (Homo sapiens)
        
        NS1 (1C) binds to Mediator complex (Homo sapiens)
        
        Mediator Complex (consensus) [nucleoplasm] (Homo sapiens)
        
        MED29 [nucleoplasm] (Homo sapiens)
        
        Mediator:NS1 [nucleoplasm] (Homo sapiens)
        
        Mediator Complex (consensus) [nucleoplasm] (Homo sapiens)
        
        MED29 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9NX70 MED29

Gene Names

MED29, IXL

Chain

initiator methionine:, chain:2-200

Reference Genes

BioGPS Gene:55588 MED29

COSMIC (genes):MED29 MED29

CTD Gene:55588 MED29

dbSNP Gene:55588 MED29

ENSEMBL:ENSG00000063322 MED29

HGNC:23074 MED29

KEGG:hsa:55588 MED29

Monarch:55588 MED29

NCBI Gene:55588 MED29

OMIM:612914 MED29

UCSC:Q9NX70 MED29

Reference Transcript

Other Identifiers

11727365_a_at

11727366_x_at

11727367_x_at

11727368_x_at

11749859_a_at

16861987

225708_3p_at

225708_PM_at

225708_at

3832965

3832966

3832967

3832968

3832969

3832970

3832971

3832972

3832973

3832974

3832975

3832976

3832977

55588

56971_f_at

62258_r_at

8028645

84225_at

86438_at

91019_at

A_23_P336929

A_24_P93887

A_32_P138330

GE56679

GO:0003712

GO:0005515

GO:0005634

GO:0005654

GO:0006355

GO:0006357

GO:0016592

GO:0032968

GO:0043226

GO:0051123

GO:0060090

GO:0060261

GO:0065003

GO:0070847

GO:0140110

HMNXSV003039516

Hs.164649.0.S1_3p_at

Hs.164649.0.S1_3p_x_at

ILMN_1728360

PH_hs_0031948

TC19000543.hg

Participates

as a component of

Mediator Complex (consensus) [nucleoplasm] (Homo sapiens)

Cross References

OpenTargets

ENSG00000063322

ENSEMBL

ENSP00000472501, ENST00000315588, ENST00000594368, ENSG00000063322, ENSP00000314343

HPA

ENSG00000063322-MED29

GeneCards

MED29

PRO

Q9NX70

Pharos - Targets

Q9NX70

GlyGen

Q9NX70

PDB

7LBM, 8GXS, 8GXQ, 7ENJ, 7ENC, 7ENA, 8TQW, 8TRH, 7EMF, 8T9D

Interactors (25)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49336 CDK8	1	CDK8 [nucleoplasm] (R-HSA-212440)	0.886	13
UniProt:Q9BTT4 MED10	1	MED10 [nucleoplasm] (R-HSA-212410)	0.867	12
UniProt:Q9H944 MED20	1	MED20 [nucleoplasm] (R-HSA-212428)	0.847	11
UniProt:O75586 MED6	1	MED6 [nucleoplasm] (R-HSA-212359)	0.802	7
UniProt:Q96G25 MED8	1	MED8 [nucleoplasm] (R-HSA-556784)	0.788	8
UniProt:Q15648 MED1	1	MED1 [nucleoplasm] (R-HSA-212445)	0.788	7
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.788	9
UniProt:Q9NVC6 MED17	1	MED17 [nucleoplasm] (R-HSA-212401)	0.788	8
UniProt:O43513 MED7	1	MED7 [nucleoplasm] (R-HSA-212430)	0.788	7
UniProt:Q9Y3C7 MED31	1	MED31 [nucleoplasm] (R-HSA-212429)	0.725	7
UniProt:O95402 MED26	1	MED26 [nucleoplasm] (R-HSA-556783)	0.725	8
UniProt:Q93074 MED12	1	MED12 [nucleoplasm] (R-HSA-212343)	0.725	6
UniProt:Q9ULK4 MED23	1	MED23 [nucleoplasm] (R-HSA-556823)	0.706	6
UniProt:Q9UHV7 MED13	1	MED13 [nucleoplasm] (R-HSA-212391)	0.643	5
UniProt:O60244 MED14	1	MED14 [nucleoplasm] (R-HSA-212441)	0.643	6
UniProt:Q96RN5 MED15	1	MED15 [nucleoplasm] (R-HSA-556827)	0.643	5
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.643	5
UniProt:Q9Y2X0 MED16	1	MED16 [nucleoplasm] (R-HSA-556802)	0.643	5
UniProt:Q6P2C8 MED27	1	MED27 [nucleoplasm] (R-HSA-556761)	0.643	6
UniProt:O75448 MED24	1	MED24 [nucleoplasm] (R-HSA-212331)	0.643	5
UniProt:Q96HR3 MED30	1	MED30 [nucleoplasm] (R-HSA-212398)	0.643	5
UniProt:Q71SY5 MED25	1	MED25 [nucleoplasm] (R-HSA-212414)	0.643	5
UniProt:A1L4H1 SSC5D	1	SSC5D [extracellular region] (R-HSA-8878615)	0.556	3
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.527	2
UniProt:O15392 BIRC5	3	BIRC5 [cytosol] (R-HSA-50851) BIRC5 [nucleoplasm] (R-HSA-4655344) ub-BIRC5 [cytosol] (R-HSA-8955933)	0.527	2