Phase 2 - plateau phase

Stable Identifier
R-HSA-5576893
Type
Pathway
Species
Homo sapiens
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Phase 2 of the cardiac action potential is the plateau phase which is sustained by a balance of Ca2+ influx through L-type Ca2+ channels (LTCCs) and K+ efflux through the slow delayed rectifier K+ channel 1 (KCNQ1). This phase sustains muscle contraction (Park & Fishman 2011, Grant 2009).

Literature References
PubMed ID Title Journal Year
19808464 Cardiac ion channels

Grant, AO

Circ Arrhythm Electrophysiol 2009
21357845 The cardiac conduction system

Park, DS, Fishman, GI

Circulation 2011
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Orthologous Events
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