IRAK4 E402TER [cytosol]

Stable Identifier
R-HSA-5602517
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
IRAK4 E402X
IRAK4 E402TER [cytosol] icon
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
17893200 Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity

Ku, CL, von Bernuth, H, Picard, C, Zhang, SY, Chang, HH, Yang, K, Chrabieh, M, Issekutz, AC, Cunningham, CK, Gallin, J, Holland, SM, Roifman, C, Ehl, S, Smart, J, Tang, M, Barrat, FJ, Levy, O, McDonald, D, Day-Good, NK, Miller, R, Takada, H, Hara, T, Al-Hajjar, S, Al-Ghonaium, A, Speert, D, Sanlaville, D, Li, X, Geissmann, F, Vivier, E, MarĂ³di, L, Garty, BZ, Chapel, H, Rodriguez-Gallego, C, Bossuyt, X, Abel, L, Puel, A, Casanova, JL

J. Exp. Med. 2007
External Reference Information
External Reference
Gene Names
IRAK4
Chain
chain:1-460
Other Identifiers
0002370333
11734066_x_at
11734067_a_at
11740649_a_at
11742042_a_at
16750277
219618_3p_at
219618_at
3412297
3412299
3412302
3412306
3412307
3412308
3412309
3412311
3412316
3412317
3412318
3412320
3412321
3412322
3412323
3412324
3412325
3412326
3412327
3412328
3412329
3412330
51135
7954969
81368_at
A_23_P13978
A_24_P158903
GE58687
GE595587
GO:0000166
GO:0000287
GO:0001816
GO:0002224
GO:0002376
GO:0002446
GO:0002755
GO:0003674
GO:0004672
GO:0004674
GO:0005149
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005737
GO:0005768
GO:0005829
GO:0005886
GO:0006464
GO:0006468
GO:0006950
GO:0007165
GO:0007254
GO:0008150
GO:0008283
GO:0010008
GO:0016301
GO:0016310
GO:0016740
GO:0019221
GO:0031410
GO:0034162
GO:0035556
GO:0040011
GO:0043123
GO:0043167
GO:0043226
GO:0045087
GO:0048661
GO:0048870
GO:0070498
GO:1990266
ILMN_1692352
TC12000325.hg
g7705840_3p_x_at
Participant Of
Other forms of this molecule
Modified Residues
Name
L-glutamic acid 402 replaced with unknown
Coordinate
402
PsiMod
A protein modification that effectively removes or replaces an L-glutamic acid.
Interactors (11)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q99836 MYD88  9 0.922 15
 UniProt:Q96FA3 PELI1  2 0.775 6
 UniProt:Q99836-1 MYD88      0.75 9
 UniProt:O43187 IRAK2  6 0.711 6
 UniProt:Q9HAT8 PELI2  2 0.593 3
 UniProt:Q9UBH0 IL36RN  1 0.556 3
 UniProt:Q96LX8 ZNF597  1 0.556 3
 UniProt:Q9C029 TRIM7      0.556 3
 UniProt:P51617 IRAK1  14 0.547 2
 UniProt:P58753 TIRAP  2 0.499 2
 UniProt:Q15109 AGER  1 0.462 4
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