MyD88 E65del [cytosol]

Stable Identifier
R-HSA-5602598
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Icon
MyD88 E65del [cytosol] icon
MyD88 E65del [cytosol] icon
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
23002119 IgM+IgD+CD27+ B cells are markedly reduced in IRAK-4-, MyD88-, and TIRAP- but not UNC-93B-deficient patients

Weller, S, Bonnet, M, Delagreverie, H, Israel, L, Chrabieh, M, Maródi, L, Rodriguez-Gallego, C, Garty, BZ, Roifman, C, Issekutz, AC, Zitnik, SE, Hoarau, C, Camcioglu, Y, Vasconcelos, J, Rodrigo, C, Arkwright, PD, Cerutti, A, Meffre, E, Zhang, SY, Alcais, A, Puel, A, Casanova, JL, Picard, C, Weill, JC, Reynaud, CA

Blood 2012
External Reference Information
External Reference
UniProt:Q99836 MYD88
Gene Names
MYD88
Chain
chain:1-296
Reference Genes
BioGPS Gene:4615 MYD88
COSMIC (genes):MYD88 MYD88
CTD Gene:4615 MYD88
dbSNP Gene:4615 MYD88
ENSEMBL:ENSG00000172936 MYD88
HGNC:7562 MYD88
KEGG Gene (Homo sapiens):4615 MYD88
Monarch:4615 MYD88
NCBI Gene:4615 MYD88
OMIM:602170 MYD88
UCSC:Q99836 MYD88
Reference Transcript
Other Identifiers
0001400128
11720623_a_at
11720624_a_at
11747538_a_at
11747539_x_at
16939127
209124_at
2617564
2617565
2617566
2617567
2617570
2617572
2617574
2617576
2617577
2617578
2JS7
2Z5V
38369_at
3MOP
4615
4DOM
4EO7
8078729
9104
A0A0A0MS70
A0A0A0MSI9
A0A3B3ITY3
A0A3F2YP85
A_14_P101666
A_14_P118253
A_23_P362659
A_23_P92140
AAB49967
AAC50954
AAH13589
AAP36040
AB446470
AK296570
AK296716
AK298650
AK298666
AP006309
BAG55247
BAG59190
BAG59306
BAG60822
BAG60834
BC013589
BI524129
BT007376
CAB009104
CH471055
EAW64521
ENSG00000172936
ENSP00000379625
ENSP00000389979
ENSP00000417848
ENST00000396334
ENST00000396334.8
ENST00000424893
ENST00000424893.6
ENST00000495303
ENST00000495303.6
EntrezGene:4615
EntrezGene:MYD88
g1763090_3p_at
GE59370
GO:0002224
GO:0002376
GO:0002755
GO:0003674
GO:0005123
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005768
GO:0005829
GO:0005886
GO:0006810
GO:0006909
GO:0006915
GO:0006950
GO:0006954
GO:0007165
GO:0007166
GO:0008063
GO:0008150
GO:0008219
GO:0009056
GO:0009058
GO:0010008
GO:0010628
GO:0016192
GO:0031410
GO:0032481
GO:0032740
GO:0032747
GO:0032755
GO:0032757
GO:0034162
GO:0034641
GO:0034655
GO:0035325
GO:0042742
GO:0042802
GO:0043066
GO:0043123
GO:0043226
GO:0043621
GO:0045087
GO:0050727
GO:0050830
GO:0051092
GO:0060337
GO:0070498
GO:0070555
GO:0070935
GO:0070976
GO:0071260
GO:0140052
GO:1900017
H0Y4G9
HGNC:7562
ILMN_1738523
IPR000157
IPR000488
IPR011029
IPR017281
IPR034249
IPR035897
LRG_157
MIM:153600
MIM:602170
MIM:612260
MYD88
MYD88-201
MYD88-205
MYD88-211
NM_001172566
NM_001172568
NP_001166037
NP_001166039
PF00531
PF01582
PH_hs_0004695
SM00005
SM00255
TC03000187.hg
U70451
U70451_at
U84408
UPI000012FAD4
UPI00003E4796
UPI0003F057AC
Participant Of
hasCandidate
Other forms of this molecule
MYD88 [cytosol]
MYD88 [plasma membrane]
MYD88 [cytosol]
MYD88 [endosome membrane]
MyD88 S34Y [cytosol]
MyD88 L93P [cytosol]
MyD88 E52del [cytosol]
MyD88 R196C [cytosol]
Modified Residues
Name
Deletion of residues 65 to 65
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
PDB
Interactors (24)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q99836 MYD88  9 0.951 38
 UniProt:Q9NWZ3 IRAK4  9 0.849 12
 UniProt:P58753 TIRAP  2 0.819 8
 UniProt:O43791 SPOP  1 0.786 7
 UniProt:O00206 TLR4  2 0.758 4
 UniProt:O60603 TLR2  2 0.737 4
 UniProt:O14836 TNFRSF13B  1 0.692 12
 UniProt:P51617 IRAK1  14 0.641 3
 UniProt:Q6SZW1 SARM1      0.622 5
 UniProt:P10599 TXN  4 0.602 4
 UniProt:Q8NF50 DOCK8  1 0.576 3
 UniProt:Q13158 FADD  1 0.573 3
 UniProt:Q69FE3 Q69FE3      0.556 5
 UniProt:P38340 NTM1      0.556 3
 UniProt:P84022 SMAD3  12 0.543 3
 UniProt:Q93009 USP7  2 0.543 3
 UniProt:Q8IUQ4 SIAH1  1 0.543 3
 UniProt:Q9UGK3 STAP2  2 0.524 3
 UniProt:P13682 ZNF35      0.488 2
 UniProt:Q8NFW5 DMBX1      0.488 2
 UniProt:P78317 RNF4  2 0.488 2
 UniProt:Q96HA8 NTAQ1      0.488 2
 UniProt:Q6IQ16 SPOPL  1 0.488 2
 UniProt:Q15109 AGER  1 0.462 8