Expression of FABP4 (aP2)

Stable Identifier
R-HSA-560510
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
lipid droplet
Locations in the PathwayBrowser
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Summation

The FABP4 gene is transcribed to yield mRNA and the mRNA is translated to yield protein. Expression of FABP4 is activated during adipogenesis.

Literature References
PubMed ID Title Journal Year
15273253 Human adipocyte fatty acid-binding protein (aP2) gene promoter-driven reporter assay discriminates nonlipogenic peroxisome proliferator-activated receptor gamma ligands

Rival, Y, Stennevin, A, Puech, L, Rouquette, A, Cathala, C, Lestienne, F, Dupont-Passelaigue, E, Patoiseau, JF, Wurch, T, Junquéro, D

J Pharmacol Exp Ther 2004
20101261 Human fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRalpha in human UCP1 expression

Morganstein, DL, Wu, P, Mane, MR, Fisk, NM, White, R, Parker, MG

Cell Res 2010
19115207 A-FABP, a candidate progression marker of human transitional cell carcinoma of the bladder, is differentially regulated by PPAR in urothelial cancer cells

Boiteux, G, Lascombe, I, Roche, E, Plissonnier, ML, Clairotte, A, Bittard, H, Fauconnet, S

Int J Cancer 2009
10425206 PPARgamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytes

Pelton, PD, Zhou, L, Demarest, KT, Burris, TP

Biochem Biophys Res Commun 1999
Participants
Input
Output
Participant Of
hasEvent
This entity is regulated by
Positive Regulation
Authored
May, B  (2010-03-23)
Reviewed
D'Eustachio, P  (2009-05-27)
Sethi, JK  (2011-02-10)