Reactome | Expression of FABP4 (aP2)

Stable Identifier

R-HSA-560510

Type

Reaction [BlackBoxEvent]

Species

Homo sapiens

Compartment

lipid droplet

Locations in the PathwayBrowser

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Summation

The FABP4 gene is transcribed to yield mRNA and the mRNA is translated to yield protein. Expression of FABP4 is activated during adipogenesis.

Literature References

PubMed ID	Title	Journal	Year
15273253	Human adipocyte fatty acid-binding protein (aP2) gene promoter-driven reporter assay discriminates nonlipogenic peroxisome proliferator-activated receptor gamma ligands	J Pharmacol Exp Ther	2004
20101261	Human fetal mesenchymal stem cells differentiate into brown and white adipocytes: a role for ERRalpha in human UCP1 expression	Cell Res	2010
19115207	A-FABP, a candidate progression marker of human transitional cell carcinoma of the bladder, is differentially regulated by PPAR in urothelial cancer cells	Int J Cancer	2009
10425206	PPARgamma activation induces the expression of the adipocyte fatty acid binding protein gene in human monocytes	Biochem Biophys Res Commun	1999

Participants

Input

Output

Participant Of

hasEvent

This entity is regulated by

Positive Regulation