K63polyUb-34,158-p-T178,184,187,S192-TAK1 [cytosol]

Stable Identifier
R-HSA-5607649
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
K63polyUb-34,158-p-T178,184,187,S192-MAP3K7
K63polyUb-34,158-p-T178,184,187,S192-TAK1 [cytosol] icon
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
MAP3K7, TAK1
Chain
chain:1-606
Other Identifiers
11736829_a_at
11736830_s_at
11741475_a_at
11741476_x_at
11742225_a_at
11743919_a_at
11750993_x_at
17021754
206853_PM_s_at
206853_s_at
206854_PM_s_at
206854_s_at
211536_PM_x_at
211536_x_at
211537_PM_x_at
211537_x_at
2964772
2964773
2964774
2964775
2964776
2964777
2964778
2964779
2964780
2964782
2964783
2964784
2964786
2964790
2964799
2964802
2964804
2964805
2964807
2964808
2964809
2964811
2964812
2964813
2964814
2964819
2964820
2964821
2964822
36905_at
53270_s_at
6885
8128260
86022_at
A_23_P500773
GE56544
GE80617
GO:0000165
GO:0000166
GO:0000287
GO:0001223
GO:0001666
GO:0002223
GO:0002376
GO:0002726
GO:0002753
GO:0002755
GO:0003824
GO:0004672
GO:0004674
GO:0004707
GO:0004709
GO:0005114
GO:0005515
GO:0005524
GO:0005634
GO:0005694
GO:0005737
GO:0005768
GO:0005829
GO:0005886
GO:0006325
GO:0006338
GO:0006468
GO:0006914
GO:0006915
GO:0006954
GO:0006955
GO:0007165
GO:0007179
GO:0007249
GO:0007250
GO:0007252
GO:0007254
GO:0008349
GO:0010008
GO:0010508
GO:0010629
GO:0012501
GO:0016020
GO:0016239
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0030971
GO:0031410
GO:0031625
GO:0032743
GO:0034138
GO:0034142
GO:0035173
GO:0035666
GO:0036211
GO:0038066
GO:0038095
GO:0038172
GO:0038173
GO:0042742
GO:0042802
GO:0043123
GO:0043226
GO:0043276
GO:0043410
GO:0043507
GO:0045787
GO:0045793
GO:0046872
GO:0048870
GO:0050852
GO:0051403
GO:0070423
GO:0070498
GO:0071356
GO:0071456
GO:0071560
GO:0097110
GO:0098542
GO:0106310
GO:0120283
GO:0140096
GO:0140297
GO:0140672
GO:1901224
GO:1904385
GO:1904707
GO:1904754
GO:1990450
GO:1990776
HMNXSV003034824
Hs.7510.0.S2_3p_a_at
ILMN_1810176
ILMN_2379326
PH_hs_0028131
PH_hs_0035759
TC06001948.hg
g4507360_3p_a_at
g8978251_3p_a_at
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
ubiquitinylated lysine (K63polyUb [cytosol]) at 34
Coordinate
34
Modification
K63polyUb [cytosol]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Name
ubiquitinylated lysine (K63polyUb [cytosol]) at 158
Coordinate
158
Modification
K63polyUb [cytosol]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Name
O-phospho-L-threonine at 178
Coordinate
178
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 184
Coordinate
184
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-threonine at 187
Coordinate
187
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 192
Coordinate
192
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
ZINC - Investigational
GeneCards
Pharos - Targets
ZINC - Predictions - Purchasable
Orphanet
HMDB Protein
Interactors (20)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9NYJ8 TAB2  4 0.91 8
 UniProt:Q15750 TAB1  6 0.899 10
 UniProt:Q8N5C8 TAB3  3 0.773 5
 UniProt:Q9UQF2 JIP1      0.723 11
 UniProt:O14733 MAP2K7  4 0.674 3
 UniProt:Q9Y4K3 TRAF6  8 0.669 3
 UniProt:Q16543 CDC37  1 0.669 4
 UniProt:O14920 IKBKB  3 0.657 6
 UniProt:P0CG48 UBC  20 0.656 4
 UniProt:O15111 CHUK  4 0.65 3
 UniProt:B5Z6S0 B5Z6S0      0.602 4
 UniProt:O00743 PPP6C  2 0.602 4
 UniProt:Q9UBE8 NLK  3 0.569 3
 UniProt:P40763 STAT3  12 0.558 4
 UniProt:P0DTC9 N  13 0.556 4
 UniProt:Q04917 YWHAH  1 0.527 2
 UniProt:Q96PV0 SYNGAP1  1 0.527 3
 UniProt:Q13451 FKBP5  2 0.527 2
 UniProt:Q9UKE5 TNIK  1 0.499 3
 UniProt:P15311 EZR  3 0.483 2
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