Reactome | RELB [nucleoplasm]

RELB [nucleoplasm]

Stable Identifier

R-HSA-5607656

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcription factor RelB, RELB_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q01201 RELB

Gene Names

RELB

Chain

chain:1-579

Reference Genes

BioGPS Gene:5971 RELB

COSMIC (genes):RELB RELB

CTD Gene:5971 RELB

dbSNP Gene:5971 RELB

ENSEMBL:ENSG00000104856 RELB

ENSEMBL_homo_sapiens_GENE:ENSG00000104856.15 RELB

HGNC:9956 RELB

KEGG Gene (Homo sapiens):5971 RELB

Monarch:5971 RELB

NCBI Gene:5971 RELB

OMIM:604758 RELB

UCSC:Q01201 RELB

Reference Transcript

RefSeq:NM_006509.3 RELB

Other Identifiers

11722141_at

16863168

205205_PM_at

205205_at

3835967

3835968

3835969

3835971

3835972

3835973

3835974

3835975

3835977

3835978

3835980

3835981

3835982

570_at

5971

8029580

A_23_P55706

GE58104

GO:0000785

GO:0000978

GO:0000981

GO:0002376

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0006351

GO:0006355

GO:0006954

GO:0007249

GO:0010468

GO:0017053

GO:0019882

GO:0019901

GO:0023052

GO:0030098

GO:0030154

GO:0032688

GO:0032922

GO:0032991

GO:0034097

GO:0038061

GO:0042088

GO:0042802

GO:0043011

GO:0043226

GO:0045063

GO:0045087

GO:0045202

GO:0045892

GO:0045944

GO:0048511

GO:0048856

GO:0071159

GO:0071470

GO:0098542

GO:0140110

HMNXSV003047976

ILMN_1811258

M83221_at

PH_hs_0029714

PH_hs_0032608

TC19000638.hg

g5730006_3p_at

g5730006_3p_x_at

Participates

as a component of

as an input of

p-S276-RELA binds RELB (Homo sapiens)

Other forms of this molecule

RELB [cytosol]

Inferred To

Relb [nucleoplasm] (Mus musculus)

Relb [nucleoplasm] (Rattus norvegicus)

RELB [nucleoplasm] (Bos taurus)

RELB [nucleoplasm] (Canis familiaris)

RELB [nucleoplasm] (Sus scrofa)

dl [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_006500.2

Guide to Pharmacology - Targets

3284

OpenTargets

ENSG00000104856

GeneCards

Q01201

HPA

ENSG00000104856-RELB

Ensembl

ENSP00000221452, ENSG00000104856, ENST00000221452

PRO

Q01201

Pharos - Targets

Q01201

PDB

8G8R

Interactors (15)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P19838 NFKB1	8	NFKB1(1-968) [specific granule lumen] (R-HSA-6799557) NFKB1(1-968) [extracellular region] (R-HSA-6806304) NFKB1(1-968) [secretory granule lumen] (R-HSA-6801004) NFKB1(1-433) [cytosol] (R-HSA-168168) NFKB1(1-433) [nucleoplasm] (R-HSA-177655) NFKB1(1-968) [cytosol] (R-HSA-451607) p-S927,S932-NFKB1(1-968) [cytosol] (R-HSA-451611) 3xUb-p-S927,S932-NFKB1(1-968) [cytosol] (R-HSA-451619)	0.865	8
UniProt:Q00653 NFKB2	6	monoSUMO1-K90,K298,K689,K863-NFKB2(1-900) [cytosol] (R-HSA-4755500) NFKB2(1-900) [cytosol] (R-HSA-2677931) K48-polyUb-p-7S-p100 [cytosol] (R-HSA-5607636) p-7S-p100 [cytosol] (R-HSA-5607629) NFKB2(1-454) [cytosol] (R-HSA-168144) NFKB2(1-454) [nucleoplasm] (R-HSA-177674)	0.744	6
UniProt:Q04206 RELA	7	MeK310-RELA [nucleoplasm] (R-HSA-8865233) p-S536-RELA [nucleoplasm] (R-HSA-9861499) p-S276,5xAcK-RELA [nucleoplasm] (R-HSA-5660642) p-S276-RELA [nucleoplasm] (R-HSA-5624468) polySUMO3-K37,K122,K123-RELA [nucleoplasm] (R-HSA-4755466) RELA [cytosol] (R-HSA-168172) RELA [nucleoplasm] (R-HSA-177676)	0.706	5
UniProt:O00221 NFKBIE	3	NFKBIE [cytosol] (R-HSA-1168580) p-S157,S161-NFKBIE [cytosol] (R-HSA-1168561) p-S157,S161-Ub-NFKBIE [cytosol] (R-HSA-1168563)	0.669	4
UniProt:P25963 NFKBIA	9	PolyUb-NFKBIA [cytosol] (R-HSA-6782960) NFKBIA [cytosol] (R-HSA-168151) p-S32,S36-NFKBIA [cytosol] (R-HSA-177677) Ub-K21,22-p-S32,S36-NFKBIA [cytosol] (R-HSA-1168581) NFKBIA [nucleoplasm] (R-HSA-4656929) monoSUMO1-K21-NFKBIA [nucleoplasm] (R-HSA-4656935) NFKBIA S32I [cytosol] (R-HSA-5228846) NFKBIA F2_M37del [cytosol] (R-HSA-9630119) NFKBIA M37K [cytosol] (R-HSA-5228805)	0.669	4
UniProt:Q04206-2 RELA			0.564	2
UniProt:Q96GM5 SMARCD1	1	SMARCD1 [nucleoplasm] (R-HSA-389255)	0.564	2
UniProt:Q92922 SMARCC1	1	SMARCC1 [nucleoplasm] (R-HSA-389257)	0.564	2
UniProt:Q92925 SMARCD2	1	SMARCD2 [nucleoplasm] (R-HSA-5225626)	0.564	2
UniProt:P49841 GSK3B	4	GSK3B del304-316 [cytosol] (R-HSA-5339682) GSK3B [nucleoplasm] (R-HSA-2022823) p-S9-GSK3B [cytosol] (R-HSA-3149577) GSK3B [cytosol] (R-HSA-2997551)	0.544	4
UniProt:Q01459 DIAC			0.527	3
UniProt:Q04864 REL	2	REL [cytosol] (R-HSA-1168579) REL [nucleoplasm] (R-HSA-1168585)	0.527	3
UniProt:Q9Y2M5 KLHL20	1	KLHL20 [cytosol] (R-HSA-976032)	0.527	2
UniProt:Q8NFZ5 TNIP2	1	TNIP2 [cytosol] (R-HSA-451661)	0.527	3
UniProt:Q8N668 COMMD1	2	COMMD1 [nucleoplasm] (R-HSA-8955094) COMMD1 [cytosol] (R-HSA-8955110)	0.499	2

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